CYCLOTHIALIDINE, A NOVEL DNA GYRASE INHIBITOR .1. SCREENING, TAXONOMY, FERMENTATION AND BIOLOGICAL-ACTIVITY

被引：33

作者：

WATANABE, J

NAKADA, N

SAWAIRI, S

SHIMADA, H

OHSHIMA, S

KAMIYAMA, T

ARISAWA, M

机构：

[1] Nippon Roche Research Center, Kamakura, Kanagawa 247

来源：

JOURNAL OF ANTIBIOTICS | 1994年 / 47卷 / 01期

关键词：

D O I：

10.7164/antibiotics.47.32

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Streptomyces filipinensis NR 0484 produced a new DNA gyrase inhibitor, cyclothialidine(1 similar to 3) . It showed potent activity against DNA gyrases from Escherichia coli and Micrococcus luteus.

引用

页码：32 / 36

页数：5

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