TRIMETHOPRIM BINDING TO BACTERIAL AND MAMMALIAN DIHYDROFOLATE-REDUCTASE - A COMPARISON BY PROTON AND C-13 NUCLEAR MAGNETIC-RESONANCE

被引：29

作者：

BIRDSALL, B

ROBERTS, GCK

FEENEY, J

DANN, JG

BURGEN, ASV

机构：

[1] NATL INST MED RES,DIV MOLEC PHARMACOL,LONDON NW7 1AA,ENGLAND

[2] WELLCOME RES LABS,BECKENHAM BR3 3BS,KENT,ENGLAND

来源：

BIOCHEMISTRY | 1983年 / 22卷 / 24期

关键词：

D O I：

10.1021/bi00293a022

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：5597 / 5604

页数：8

共 39 条

[11]

CAYLEY PJ, 1979, BIOCHEMISTRY-US, V18, P3886, DOI 10.1021/bi00585a008

[12]

CAYLEY PJ, 1980, THESIS COUNCIL NATIO

[13] PROTONATION OF METHOTREXATE BOUND TO THE CATALYTIC SITE OF DIHYDROFOLATE-REDUCTASE FROM LACTOBACILLUS-CASEI [J].

COCCO, L ;

TEMPLE, C ;

MONTGOMERY, JA ;

LONDON, RE ;

BLAKLEY, RL .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1981, 100 (01) :413-419

[14] LARGE-SCALE PURIFICATION AND CHARACTERIZATION OF DIHYDROFOLATE-REDUCTASE FROM A METHOTREXATE-RESISTANT STRAIN OF LACTOBACILLUS-CASEI [J].

DANN, JG ;

OSTLER, G ;

BJUR, RA ;

KING, RW ;

SCUDDER, P ;

TURNER, PC ;

ROBERTS, GCK ;

BURGEN, ASV ;

HARDING, NGL .

BIOCHEMICAL JOURNAL, 1976, 157 (03) :559-571

[15] QUANTITATIVE STRUCTURE-SELECTIVITY RELATIONSHIPS - COMPARISON OF THE INHIBITION OF ESCHERICHIA-COLI AND BOVINE LIVER DIHYDROFOLATE-REDUCTASE BY 5-(SUBSTITUTED-BENZYL)-2,4-DIAMINOPYRIMIDINES [J].

DIETRICH, SW ;

BLANEY, JM ;

REYNOLDS, MA ;

JOW, PYC ;

HANSCH, C .

JOURNAL OF MEDICINAL CHEMISTRY, 1980, 23 (11) :1205-1212

[16] USE OF TRANSFERRED NUCLEAR OVERHAUSER EFFECT MEASUREMENT TO COMPARE BINDING OF CO-ENZYME ANALOGS TO DIHYDROFOLATE-REDUCTASE [J].

FEENEY, J ;

BIRDSALL, B ;

ROBERTS, GCK ;

BURGEN, ASV .

BIOCHEMISTRY, 1983, 22 (03) :628-633

[17] H-1 NUCLEAR MAGNETIC-RESONANCE STUDIES OF TYROSINE RESIDUES OF SELECTIVELY DEUTERATED LACTOBACILLUS-CASEI DIHYDROFOLATE-REDUCTASE [J].

FEENEY, J ;

ROBERTS, GCK ;

BIRDSALL, B ;

GRIFFITHS, DV ;

KING, RW ;

SCUDDER, P ;

BURGEN, A .

PROCEEDINGS OF THE ROYAL SOCIETY SERIES B-BIOLOGICAL SCIENCES, 1977, 196 (1124) :267-290

[18]

FINLAND M, 1973, J INFECT DIS S, V128, P5433

[19] STUDY OF MODERATELY RAPID CHEMICAL EXCHANGE REACTIONS BY MEANS OF NUCLEAR MAGNETIC DOUBLE RESONANCE [J].

FORSEN, S ;

HOFFMAN, RA .

JOURNAL OF CHEMICAL PHYSICS, 1963, 39 (11) :2892-&

[20]

HITCHINGS GH, 1983, HDB EXP PHARMAKOL, V64

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