ON THE USE OF COMBINATORIAL ANTIBODY LIBRARIES TO CLONE THE FOSSIL RECORD OF AN INDIVIDUALS IMMUNE-RESPONSE

被引：22

作者：

LERNER, RA ^{[1
]}

BARBAS, CF ^{[1
]}

KANG, AS ^{[1
]}

BURTON, DR ^{[1
]}

机构：

[1] SCRIPPS RES INST, DEPT MOLEC BIOL, LA JOLLA, CA 92037 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1991年 / 88卷 / 21期

关键词：

PASSIVE ANTIBODY; AIDS; IMMUNOLOGICAL MEMORY; CATALYTIC ANTIBODIES;

D O I：

10.1073/pnas.88.21.9705

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

For about the last century the record of immunological events could only be obtained from serum proteins. We suggest that in the future this will change and the far more detailed nucleic acid record will provide new insights into immunological processes as well as selective access to the complete repertoire.

引用

页码：9705 / 9706

页数：2

共 14 条

[1] ASSEMBLY OF COMBINATORIAL ANTIBODY LIBRARIES ON PHAGE SURFACES - THE GENE-III SITE
BARBAS, CF
KANG, AS
LERNER, RA
BENKOVIC, SJ
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (18) : 7978 - 7982
[2] IS T-CELL MEMORY MAINTAINED BY CROSS-REACTIVE STIMULATION
BEVERLEY, PCL
[J]. IMMUNOLOGY TODAY, 1990, 11 (06): : 203 - 205
[3] HUMAN AND MOUSE MONOCLONAL-ANTIBODIES BY REPERTOIRE CLONING
BURTON, DR
[J]. TRENDS IN BIOTECHNOLOGY, 1991, 9 (05) : 169 - 175
[4] BURTON DR, 1991, IN PRESS P NATL ACAD
[5] INFLUENZA-VIRUS HEMAGGLUTININ-SPECIFIC ANTIBODIES ISOLATED FROM A COMBINATORIAL EXPRESSION LIBRARY ARE CLOSELY RELATED TO THE IMMUNE-RESPONSE OF THE DONOR
CATON, AJ
KOPROWSKI, H
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (16) : 6450 - 6454
[6] LONG-TERM MORTALITY AFTER A SINGLE TREATMENT COURSE WITH X-RAYS IN PATIENTS TREATED FOR ANKYLOSING-SPONDYLITIS
DARBY, SC
DOLL, R
GILL, SK
SMITH, PG
[J]. BRITISH JOURNAL OF CANCER, 1987, 55 (02) : 179 - 190
[7] GENERATION OF A LARGE COMBINATORIAL LIBRARY OF THE IMMUNOGLOBULIN REPERTOIRE IN PHAGE-LAMBDA
HUSE, WD
SASTRY, L
IVERSON, SA
KANG, AS
ALTINGMEES, M
BURTON, DR
BENKOVIC, SJ
LERNER, RA
[J]. SCIENCE, 1989, 246 (4935) : 1275 - 1281
[8] LINKAGE OF RECOGNITION AND REPLICATION FUNCTIONS BY ASSEMBLING COMBINATORIAL ANTIBODY FAB LIBRARIES ALONG PHAGE SURFACES
KANG, AS
BARBAS, CF
JANDA, KD
BENKOVIC, SJ
LERNER, RA
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (10) : 4363 - 4366
[9] PHAGE ANTIBODIES - FILAMENTOUS PHAGE DISPLAYING ANTIBODY VARIABLE DOMAINS
MCCAFFERTY, J
GRIFFITHS, AD
WINTER, G
CHISWELL, DJ
[J]. NATURE, 1990, 348 (6301) : 552 - 554
[10] MOLECULAR CHARACTERIZATION OF SINGLE MEMORY B-CELLS
MCHEYZERWILLIAMS, MG
NOSSAL, GJV
LALOR, PA
[J]. NATURE, 1991, 350 (6318) : 502 - 505

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