AN INVITRO STUDY OF POSSIBLE FOOD-DRUG INTERACTIONS OF THE CONTROLLED-RELEASE PROPRANOLOL PRODUCTS

被引：6

作者：

ELARINI, SK

SHIU, GK

SKELLY, JP

机构：

[1] US FDA,BIOPHARMACEUT RES BRANCH,WASHINGTON,DC 20204

[2] US FDA,DIV BIOPHARMACEUT,ROCKVILLE,MD 20857

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICS | 1989年 / 55卷 / 01期

关键词：

D O I：

10.1016/0378-5173(89)90272-X

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：25 / 30

页数：6

共 9 条

[1] STABLE ORAL AVAILABILITY OF SUSTAINED-RELEASE PROPRANOLOL WHEN CO-ADMINISTERED WITH HYDRALAZINE OR FOOD - EVIDENCE IMPLICATING SUBSTRATE DELIVERY RATE AS A DETERMINANT OF PRESYSTEMIC DRUG-INTERACTIONS [J].

BYRNE, AJ ;

MCNEIL, JJ ;

HARRISON, PM ;

LOUIS, W ;

TONKIN, AM ;

MCLEAN, AJ .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1984, 17 :S45-S50

[2] CONCOMITANT FOOD-INTAKE CAN INCREASE THE BIOAVAILABILITY OF PROPRANOLOL BY TRANSIENT INHIBITION OF ITS PRESYSTEMIC PRIMARY CONJUGATION [J].

LIEDHOLM, H ;

MELANDER, A .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1986, 40 (01) :29-36

[3]

LIEDHOLM H, 1983, DRUG NUTR INTERACT, V1, P293

[4] INFLUENCE OF A HIGH-FAT BREAKFAST ON THE BIOAVAILABILITY OF THEOPHYLLINE CONTROLLED-RELEASE FORMULATIONS - AN INVITRO DEMONSTRATION OF AN INVIVO OBSERVATION [J].

MATURU, PK ;

PRASAD, VK ;

WORSLEY, WN ;

SHIU, GK ;

SKELLY, JP .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1986, 75 (12) :1205-1206

[5] REDUCTION OF 1ST-PASS HEPATIC-CLEARANCE OF PROPRANOLOL BY FOOD [J].

MCLEAN, AJ ;

ISBISTER, C ;

BOBIK, A ;

DUDLEY, FJ .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1981, 30 (01) :31-34

[6]

MELANDER A, 1977, CLIN PHARMACOL THER, V22, P108

[7]

SKELLY JP, 1986, DRUG DEV IND PHARM, V12, P1117

[8]

SKELLY JP, 1986, 13TH INT S CONTR REL

[9] EFFECT OF FOOD ON HEPATIC BLOOD-FLOW - IMPLICATIONS IN THE FOOD EFFECT PHENOMENON [J].

SVENSSON, CK ;

EDWARDS, DJ ;

MAURIELLO, PM ;

BARDE, SH ;

FOSTER, AC ;

LANC, RA ;

MIDDLETON, E .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1983, 34 (03) :316-323

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