SUCCESSIVE DIARYLATION AT THE CARBON POSITIONS (2/4 AND 2/5) OF 1H-IMIDAZOLE AND ITS APPLICATION TO THE TOTAL SYNTHESIS OF NORTOPSENTIN-D

被引：37

作者：

KASWASAKI, I ^{[1
]}

YAMASHITA, M ^{[1
]}

OHTA, S ^{[1
]}

机构：

[1] KYOTO PHARMACEUT UNIV,YAMASHIMA KU,KYOTO 607,JAPAN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1994年 / 18期

关键词：

D O I：

10.1039/c39940002085

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Nortopsentin D, an antifungal 2,4-diindolylimidazole, is synthesized by use of a;successive and regioselective diarylation, in which N-protected 2,4,5-tri- and 4,5-di-bromoimidazole derivatives are treated with N-silylated 3-indolylboric acid in the presence of a palladium(o) catalyst.

引用

页码：2085 / 2086

页数：2

共 16 条

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