THE REGULATION AND EXPRESSION OF MHC CLASS-I GENES

被引：247

作者：

DAVID-WATINE, B

ISRAEL, A

KOURILSKY, P

机构：

[1] Unité de Biologie Moléculaire, Gene-U.277 INSERM UAC 115 CNRS Institut Pasteur, 75724 Paris Cédex 15

来源：

IMMUNOLOGY TODAY | 1990年 / 11卷 / 08期

关键词：

D O I：

10.1016/0167-5699(90)90114-O

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The expression of mouse MHC class I genes and their products in vivo reveals complex patterns of regulation. Different promoter elements, which are required for gene activation or modulation in response to various external stimuli, have now been characterized as well as the proteins that bind to them. As described here by Brigitte David-Watine and colleagues, the picture that has gradually emerged from these in vitro studies is of an intricate interplay of transacting factors that ultimately lead to the fine tuning of MHC class I expression in vivo. © 1990.

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页码：286 / 292

页数：7

相关论文

共 74 条

[61] INTERFERONS INCREASE TRANSCRIPTION OF A MAJOR HISTOCOMPATIBILITY CLASS-I GENE VIA A 5' INTERFERON CONSENSUS SEQUENCE [J].

SUGITA, K ;

MIYAZAKI, JI ;

APPELLA, E ;

OZATO, K .

MOLECULAR AND CELLULAR BIOLOGY, 1987, 7 (07) :2625-2630

[62]

TANAKA K, 1988, ANNU REV IMMUNOL, V6, P359

[63]

TANIGUCHI T, 1988, ANNU REV IMMUNOL, V6, P439, DOI 10.1146/annurev.iy.06.040188.002255

[64] A LOW POLYMORPHIC MOUSE H-2 CLASS-I GENE FROM THE TLA COMPLEX IS EXPRESSED IN A BROAD VARIETY OF CELL-TYPES [J].

TRANSY, C ;

NASH, SR ;

DAVID-WATINE, B ;

COCHET, M ;

HUNT, SW ;

HOOD, LE ;

KOURILSKY, P .

JOURNAL OF EXPERIMENTAL MEDICINE, 1987, 166 (02) :341-361

[65]

VERNACHIO J, 1989, J IMMUNOL, V142, P48

[66] QA-1 RESTRICTED RECOGNITION OF FOREIGN ANTIGEN BY A GAMMA-DELTA T-CELL HYBRIDOMA [J].

VIDOVIC, D ;

ROGLIC, M ;

MCKUNE, K ;

GUERDER, S ;

MACKAY, C ;

DEMBIC, Z .

NATURE, 1989, 340 (6235) :646-650

[67] DOUBLE-STRANDED-RNA ACTIVATES BINDING OF NF-KAPPA-B TO AN INDUCIBLE ELEMENT IN THE HUMAN BETA-INTERFERON PROMOTER [J].

VISVANATHAN, KV ;

GOODBOURN, S .

EMBO JOURNAL, 1989, 8 (04) :1129-1138

[68] INDUCTION OF MAJOR HISTOCOMPATIBILITY CLASS-I ANTIGENS BY INTERFERONS IN UNDIFFERENTIATED F9 CELLS [J].

WAN, YJY ;

ORRISON, BM ;

LIEBERMAN, R ;

LAZAROVICI, P ;

OZATO, K .

JOURNAL OF CELLULAR PHYSIOLOGY, 1987, 130 (02) :276-283

[69] ANALYSIS OF QA-2 ANTIGEN EXPRESSION BY PREIMPLANTATION MOUSE EMBRYOS - POSSIBLE RELATIONSHIP TO THE PREIMPLANTATION-EMBRYO-DEVELOPMENT (PED) GENE-PRODUCT [J].

WARNER, CM ;

GOLLNICK, SO ;

FLAHERTY, L ;

GOLDBARD, SB .

BIOLOGY OF REPRODUCTION, 1987, 36 (03) :611-616

[70] ORGANIZATION AND STRUCTURE OF THE QA GENES OF THE MAJOR HISTOCOMPATIBILITY COMPLEX OF THE C3H MOUSE - IMPLICATIONS FOR QA FUNCTION AND CLASS-I EVOLUTION [J].

WATTS, S ;

DAVIS, AC ;

GAUT, B ;

WHEELER, C ;

HILL, L ;

GOODENOW, RS .

EMBO JOURNAL, 1989, 8 (06) :1749-1759

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