HPLC WITH CARBOHYDRATE CARBAMATE CHIRAL PHASES - INFLUENCE OF CHIRAL PHASE-STRUCTURE ON ENANTIOSELECTIVITY

被引：65

作者：

MATLIN, SA

TIRITAN, ME

CRAWFORD, AJ

CASS, QB

BOYD, DR

机构：

[1] UNIV FED SAO CARLOS,DEPT CHEM,SAO CARLOS,SP,BRAZIL

[2] QUEENS UNIV BELFAST,SCH CHEM,BELFAST,ANTRIM,NORTH IRELAND

来源：

CHIRALITY | 1994年 / 6卷 / 02期

关键词：

AMYLOSE; CELLULOSE; PHENYLCARBAMATE; 3,5-DIMETHYLPHENYLCARBAMATE; 3,5-DIMETHOXYPHENYLCARBAMATE; TRANS-STILBENE OXIDE; CHIRAL SULFOXIDES; RESOLUTION;

D O I：

10.1002/chir.530060214

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The enantioselective resolution of trans-stilbene oxide and of 23 chiral sulfoxides was investigated on cellulose and amylose tris(arylcarbamate) stationary phases coated on aminopropylated 7 mu m spherical silica with 500 Angstrom diameter pores. Cellulose tris-(3,5 dimethylphenylcarbamate) showed good resolving power for many of the sulfoxides and amylose tris-(3,5 dimethoxyphenylcarbamate) showed advantages for the resolution of certain sulfoxides which were not separated on other phases. (C) 1994 Wiley-Liss, Inc.

引用

页码：135 / 140

页数：6

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