Genetically-modified brewing yeasts for the 21st Century. Progress to date

被引:65
作者
Hammond, JRM
机构
[1] Brf International, Redhill, Surrey, RH1 4HY, Lyttel Hall, Nutfield
关键词
yeast; brewing; Saccharomyces; genetic-modification; recombinant DNA;
D O I
10.1002/yea.320111606
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Academic studies and traditional breeding of yeasts depend upon their sporulation lifestyle. The strains used have been specially selected to sporulate readily and to mate producing new yeast types. Unfortunately brewing yeast strains do not behave in this way. They sporulate poorly, any spores which are formed are usually non-viable and any haploid strains produced are invariably non-maters. Only in recent years, with the development of recombinant-DNA techniques, has the specific breeding of new brewing yeast strains become widespread. Strains have been produced with the ability to ferment a wider range of carbohydrates, with altered flocculation properties and which produce beers with modified flavours. Many have been tested on the pilot scale and one, an amylolytic brewing yeast, has received approval for commercial use.
引用
收藏
页码:1613 / 1627
页数:15
相关论文
共 82 条
[31]  
Hinchliffe E., 1987, Proceedings, European Brewery Convention, P505
[32]  
HINCHLIFFE E, 1985, 20TH EUR BREW CONV P, P267
[33]   STABLE OVERPRODUCTION OF ISOAMYL ALCOHOL BY SACCHAROMYCES-CEREVISIAE WITH CHROMOSOME-INTEGRATED MULTICOPY LEU4 GENES [J].
HIRATA, D ;
AOKI, S ;
WATANABE, K ;
TSUKIOKA, M ;
SUZUKI, T .
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 1992, 56 (10) :1682-1683
[34]   CONSTRUCTION OF A YEAST VECTOR DIRECTING THE SYNTHESIS AND RELEASE OF BARLEY (1-]3,1-]4)-BETA-GLUCANASE [J].
JACKSON, EA ;
BALLANCE, GM ;
THOMSEN, KK .
CARLSBERG RESEARCH COMMUNICATIONS, 1986, 51 (06) :445-458
[35]   EXPRESSION OF A TRANSPOSABLE ANTIBIOTIC-RESISTANCE ELEMENT IN SACCHAROMYCES [J].
JIMENEZ, A ;
DAVIES, J .
NATURE, 1980, 287 (5785) :869-871
[36]  
Kielland-Brandt MC, 1989, P EUROPEAN BREWERY C, P37
[37]  
KNOWLES JKC, 1985, P EUROPEAN BREWERY C, P251
[38]  
KODAMA Y, 1995, J AM SOC BREW CHEM, V53, P24
[39]  
Korch C., 1991, P EUR BREW CONV C, P201
[40]  
Lancashire W. E., 1987, Proceedings, European Brewery Convention, P513