PALLADIUM-CATALYZED COUPLING OF TERMINAL ALKYNES WITH 5-(TRIFLUOROMETHANESULFONYLOXY)PYRIMIDINE NUCLEOSIDES

被引：75

作者：

CRISP, GT

FLYNN, BL

机构：

[1] Department of Organic Chemistry, University of Adelaide, Adelaide, South Australia, 5001

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1993年 / 58卷 / 24期

关键词：

D O I：

10.1021/jo00076a019

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The palladium-catalyzed couplings of terminal alkynes with 2',3',5'-tri-O-acetyl-5-(triflouromethanesulfonyloxy)uridine, 3',5'-di-O-acetyl-5-(triflouromethanesulfonyloxy)-2'-deoxyuridine, and 5-(triflouromethanesulfonyloxy)-2'-deoxyuridine have been investigated under a variety of conditions.

引用

页码：6614 / 6619

页数：6

共 34 条

[1] INHIBITION OF THYMIDYLATE SYNTHETASE BY 5-ALKYNYL-2'-DEOXYURIDYLATES
BARR, PJ
NOLAN, PA
SANTI, DV
ROBINS, MJ
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1981, 24 (12) : 1385 - 1388
[2] SYNTHESIS OF NUCLEOSIDES DERIVED FROM 5-ETHYNYLURACIL AND 5-ETHYNYL-CYTOSINE
BARR, PJ
JONES, AS
SERAFINOWSKI, P
WALKER, RT
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1978, (10): : 1263 - 1267
[3] BERGSTROM D, 1992, J SYNLETT, P179
[4] C-5 SUBSTITUTED PYRIMIDINE NUCLEOSIDES .2. SYNTHESIS VIA OLEFIN COUPLING TO ORGANOPALLADIUM INTERMEDIATES DERIVED FROM URIDINE AND 2'-DEOXYURIDINE
BERGSTROM, DE
OGAWA, MK
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1978, 100 (26) : 8106 - 8112
[5] BOBEK M, 1978, CHEM BIOL NUCLEOSIDE, P135
[6] TOTAL SYNTHESIS OF 7-IODO-2',3'-DIDEOXY-7-DEAZAPURINE NUCLEOSIDES, KEY INTERMEDIATES IN THE PREPARATION OF REAGENTS FOR THE AUTOMATED SEQUENCING OF DNA
COCUZZA, AJ
[J]. TETRAHEDRON LETTERS, 1988, 29 (33) : 4061 - 4064
[7] Coulson DR, 1971, INORG SYN, V13, P121, DOI DOI 10.1002/9780470132449.CH23
[8] PALLADIUM-CATALYZED COUPLING OF URIDINE TRIFLATE WITH ORGANOSTANNANES
CRISP, GT
FLYNN, BL
[J]. TETRAHEDRON LETTERS, 1990, 31 (09) : 1347 - 1350
[9] DECLERCQ E, 1979, P NATL ACAD SCI USA, V76, P2947, DOI 10.1073/pnas.76.6.2947
[10] NUCLEIC-ACID RELATED-COMPOUNDS .40. SYNTHESIS AND BIOLOGICAL-ACTIVITIES OF 5-ALKYNYLURACIL NUCLEOSIDES
DECLERCQ, E
DESCAMPS, J
BALZARINI, J
GIZIEWICZ, J
BARR, PJ
ROBINS, MJ
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1983, 26 (05) : 661 - 666

← 1 2 3 4 →