STEREOSELECTIVE 2-STEP CHEMICAL PREPARATION OF 1,4-DIALKYL-1,4-DIMETHOXYCYCLOHEXA-2,5-DIENES

被引：11

作者：

ALONSO, F ^{[1
]}

YUS, M ^{[1
]}

机构：

[1] UNIV ALICANTE,DEPT QUIM ORGAN,APTDO 99,E-03080 ALACANT,SPAIN

来源：

TETRAHEDRON | 1991年 / 47卷 / 35期

关键词：

D O I：

10.1016/S0040-4020(01)89749-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of p-benzoquinone (1) with several organolithium compounds (methyl-, ethyl-, n-butyl-, phenylithium) led, after hydrolysis with water, to the corresponding crude diols 4, which were successively treated with sodium hydride and methyl iodide yielding the expected 1,4-dialkyl-1,4-dimethoxycyclohexa-2,5-dienes 2a-d in a stereoselective manner. The use of a tandem process with two different organolithium reagents followed by methylation by the same procedure yielded stereoselectively the mixed 1-alkyl-4-alkyl' derivatives 2e,f.

引用

页码：7471 / 7476

页数：6

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