AN APPROACH TOWARDS THIOL MEDIATED LABELING IN THE MINOR-GROOVE OF OLIGONUCLEOTIDES

被引:14
作者
DOUGLAS, ME [1 ]
BEIJER, B [1 ]
SPROAT, BS [1 ]
机构
[1] EUROPEAN MOLEC BIOL LAB,D-69012 HEIDELBERG,GERMANY
关键词
D O I
10.1016/S0960-894X(01)80669-7
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The preparation of an appropriately protected 2'-O-(2-thioethyl)uridine phosphoramidite is reported along with its incorporation into an oligonucleotide and post-synthetic labelling.
引用
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页码:995 / 1000
页数:6
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