ACUTE EFFECTS OF 1-METHYL-4-PHENYLPYRIDINIUM ION (MPP+) ON DOPAMINE AND SEROTONIN METABOLISM IN RAT STRIATUM AS ASSAYED INVIVO BY A MICRO-DIALYSIS TECHNIQUE

被引：52

作者：

OZAKI, N

NAKAHARA, D

KANEDA, N

KIUCHI, K

OKADA, T

KASAHARA, Y

NAGATSU, T

机构：

[1] NAGOYA UNIV,COLL MED TECHNOL,DEPT PSYCHOL,NAGOYA,AICHI 464,JAPAN

[2] NAGOYA UNIV,SCH MED,DEPT BIOCHEM,NAGOYA,AICHI 466,JAPAN

来源：

JOURNAL OF NEURAL TRANSMISSION | 1987年 / 70卷 / 3-4期

关键词：

D O I：

10.1007/BF01253601

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

引用

页码：241 / 250

页数：10

共 22 条

[1] 1-METHYL-4-PHENYLPYRIDINE IS NEUROTOXIC TO THE NIGROSTRIATAL DOPAMINE PATHWAY [J].

BRADBURY, AJ ;

COSTALL, B ;

DOMENEY, AM ;

JENNER, P ;

KELLY, ME ;

MARSDEN, CD ;

NAYLOR, RJ .

NATURE, 1986, 319 (6048) :56-57

[2]

BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3

[3] A PRIMATE MODEL OF PARKINSONISM - SELECTIVE DESTRUCTION OF DOPAMINERGIC-NEURONS IN THE PARS COMPACTA OF THE SUBSTANTIA NIGRA BY N-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE [J].

BURNS, RS ;

CHIUEH, CC ;

MARKEY, SP ;

EBERT, MH ;

JACOBOWITZ, DM ;

KOPIN, IJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (14) :4546-4550

[4] THE MECHANISM OF ACTION OF MPTP AND MPP+ ON ENDOGENOUS DOPAMINE RELEASE FROM THE RAT CORPUS STRIATUM SUPERFUSED INVITRO [J].

CHANG, GD ;

RAMIREZ, VD .

BRAIN RESEARCH, 1986, 368 (01) :134-140

[5] METABOLISM OF THE NEUROTOXIC TERTIARY AMINE, MPTP, BY BRAIN MONOAMINE-OXIDASE [J].

CHIBA, K ;

TREVOR, A ;

CASTAGNOLI, N .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1984, 120 (02) :574-578

[6] ACUTE ADMINISTRATION OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) REDUCES DOPAMINE AND SEROTONIN BUT ACCELERATES NOREPINEPHRINE METABOLISM IN THE RAT-BRAIN - EFFECT OF CHRONIC PRETREATMENT WITH MPTP [J].

ENZ, A ;

HEFTI, F ;

FRICK, W .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1984, 101 (1-2) :37-44

[7] DOPAMINERGIC NEUROTOXICITY OF 1-METHYL-4-PHENYL-1,2,5,6-TETRAHYDROPYRIDINE IN MICE [J].

HEIKKILA, RE ;

HESS, A ;

DUVOISIN, RC .

SCIENCE, 1984, 224 (4656) :1451-1453

[8] EARLY AND LATE EFFECTS OF SYSTEMICALLY ADMINISTERED 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) ON TYROSINE-HYDROXYLASE ACTIVITY INVITRO AND ON TYROSINE HYDROXYLATION IN TISSUE-SLICES OF MOUSE STRIATUM [J].

HIRATA, Y ;

NAGATSU, T .

NEUROSCIENCE LETTERS, 1986, 68 (02) :245-248

[9] BRAIN DIALYSIS - INVIVO METABOLISM OF DOPAMINE AND SEROTONIN BY MONOAMINE OXIDASE-A BUT NOT OXIDASE-B IN THE STRIATUM OF UNRESTRAINED RATS [J].

KATO, T ;

DONG, B ;

ISHII, K ;

KINEMUCHI, H .

JOURNAL OF NEUROCHEMISTRY, 1986, 46 (04) :1277-1282

[10] PARTICIPATION OF BRAIN MONOAMINE-OXIDASE B FORM IN THE NEUROTOXICITY OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE - RELATIONSHIP BETWEEN THE ENZYME-INHIBITION AND THE NEUROTOXICITY [J].

KINEMUCHI, H ;

ARAI, Y ;

TOYOSHIMA, Y .

NEUROSCIENCE LETTERS, 1985, 58 (02) :195-200

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