SIMULTANEOUS DETERMINATION OF DEXAMETHASONE AND BETAMETHASONE IN PHARMACEUTICALS BY REVERSED-PHASE HPLC

被引：29

作者：

SANTOSMONTES, A ^{[1
]}

GASCOLOPEZ, AI ^{[1
]}

IZQUIERDOHORNILLOS, R ^{[1
]}

机构：

[1] UNIV COMPLUTENSE MADRID,FAC QUIM,DEPT QUIM ANALIT,E-28040 MADRID,SPAIN

来源：

CHROMATOGRAPHIA | 1994年 / 39卷 / 9-10期

关键词：

COLUMN LIQUID CHROMATOGRAPHY; GLUCOCORTICOIDS; BETAMETHASONE AND DEXAMETHASONE; PHARMACEUTICALS; TABLET PREPARATIONS;

D O I：

10.1007/BF02268276

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

An HPLC method for the simultaneous determination of the glucocorticoids betamethasone and dexamethasone is described. The method based on the separation of these compounds using a binary water-tetrahydrofuran mobile phase and a reversed-phase Hypersil C-18 column, was applied to the determination of betamethasone and dexamethasone in tablets.

引用

页码：539 / 542

页数：4

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