UNPRECEDENTED STABILITY OF DELTA-LACTONES WITH AXIAL SUBSTITUENTS RATHER THAN EQUATORIAL ONES - COMPARISON WITH THE PRELOG-DJERASSI LACTONE DERIVATIVE

被引：10

作者：

MORIMOTO, Y ^{[1
]}

MIKAMI, A ^{[1
]}

SHIRAHAMA, H ^{[1
]}

机构：

[1] HOKKAIDO UNIV,FAC SCI,DEPT CHEM,SAPPORO,HOKKAIDO 060,JAPAN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1991年 / 19期

关键词：

D O I：

10.1039/c39910001376

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A 1:1 mixture of the trisubstituted delta-lactones 11a and 11b was subjected to thermodynamically equilibrated conditions to give predominantly 11b with axial substituents rather than 11a with all equatorial ones, in contrast to the Prelog-Djerassi lactone derivatives 3a and 3b, and, further surprisingly, it has been found that the disubstituted lactone 10 also adopts a chair conformation with axial substituents.

引用

页码：1376 / 1378

页数：3

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