DETERMINATION OF SYNEPHRINE AND N-METHYLTYRAMINE IN ZHISHI AND ZHIKE (IMMATURE CITRUS-FRUITS) BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY WITH ELECTROCHEMICAL DETECTION

被引：25

作者：

KUSU, F ^{[1
]}

LI, XD ^{[1
]}

TAKAMURA, K ^{[1
]}

机构：

[1] ACAD CHINA CHINESE MED, INST CHINESE MATERIA MED, BEIJING, PEOPLES R CHINA

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 1992年 / 40卷 / 12期

关键词：

SYNEPHRINE; N-METHYLTYRAMINE; CITRUS-AURANTIUM; CHINESE CRUDE DRUG; HPLC; ELECTROCHEMICAL DETECTION;

D O I：

10.1248/cpb.40.3284

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

High-performance liquid chromatography (HPLC) with electrochemical detection was used to determine synephrine (SYN) and N-methyltyramine (NMT) in Zhishi (Kijitsu ) and Zhike (Kikoku ). This electrochemical detection method has not only specific selectivity but also very high sensitivity, thus facilitating the determination of SYN and NMT from pulverized Zhishi and Zhike samples. Zhishi and Zhike derived from Citrus aurantium produced in different districts in China were analysed. This method was found useful for evaluating the quality of a crude drug such as Citrus aurantium.

引用

页码：3284 / 3286

页数：3

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