BASIC ACTIONS OF TRANSFORMING GROWTH-FACTOR-ALPHA AND RELATED PEPTIDES

被引：14

作者：

COFFEY, RJ

GANGAROSA, LM

DAMSTRUP, L

DEMPSEY, PJ

机构：

[1] Departments of Medicine and Cell Biology, Vanderbilt University, Nashville, TN

来源：

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY | 1995年 / 7卷 / 10期

关键词：

TRANSFORMING GROWTH FACTOR-ALPHA; AEPIDERMAL GROWTH FACTOR; AMPHIREGULIN; HEPARIN-BINDING ECF-LIKE GROWTH FACTOR;

D O I：

10.1097/00042737-199510000-00003

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Transforming growth factor-alpha (TGF-alpha) and related peptides have been implicated in a wide range of biological activities, including cell growth, differentiation and acid inhibition. This chapter reviews the roles of TGF-alpha in the stomach, the insights gained into the action of the TGF-alpha a Family of growth factors from the study of polarized epithelial cells and the confirmation of events mediated by the epidermal growth factor receptor (EGFR) by the study of mice in which the EGFR has been disrupted by homologous recombination.

引用

页码：923 / 927

页数：5

共 49 条

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