GATING OF SOMATOSENSORY INPUT BY HUMAN PREFRONTAL CORTEX

被引：125

作者：

YAMAGUCHI, S ^{[1
]}

KNIGHT, RT ^{[1
]}

机构：

[1] SHIMANE MED UNIV,DIV INTERNAL MED 3,IZUMO,SHIMANE 693,JAPAN

来源：

BRAIN RESEARCH | 1990年 / 521卷 / 1-2期

关键词：

Gating; Inhibition; Prefrontal cortex; Somatosensory evoked potential;

D O I：

10.1016/0006-8993(90)91553-S

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Somatosensory evoked potentials (SEPs) to median nerve stimulation were recorded in controls and in patients with focal lesions in dorsolateral prefrontal cortex (PFCx). Unilateral PFCx lesions increased the amplitude of the P26 component generated in postcentral areas 1 and 2. The amplitudes of the N28, P45 and N67 SEP components recorded over post-rolandic and frontal electrodes were also enhanced by PFCx damage. In contrast, the N19 component generated in postcentral area 3b was unaffected by PFCx lesions. The results indicate that PFCx exerts inhibitory modulation on sensory processing that may be mediated by corticocortical PFCx-parietal connections. © 1990.

引用

页码：281 / 288

页数：8

共 47 条

[21] ELECTROPHYSIOLOGICAL STUDY OF MYOCLONUS IN MAN [J].

HALLIDAY, AM .

BRAIN, 1967, 90 :241-+

[22]

Jacobsen C. F., 1936, COMP PSYCHOL MONOGR, V13, P3

[23] INTRA-CORTICAL CONNECTIVITY OF ARCHITECTONIC FIELDS IN SOMATIC SENSORY, MOTOR AND PARIETAL CORTEX OF MONKEYS [J].

JONES, EG ;

COULTER, JD ;

HENDRY, SHC .

JOURNAL OF COMPARATIVE NEUROLOGY, 1978, 181 (02) :291-&

[24] GENERATOR MECHANISMS OF GIANT SOMATOSENSORY EVOKED-POTENTIALS IN CORTICAL REFLEX MYOCLONUS [J].

KAKIGI, R ;

SHIBASAKI, H .

BRAIN, 1987, 110 :1359-1373

[25] THE EFFECTS OF FRONTAL-CORTEX LESIONS ON EVENT-RELATED POTENTIALS DURING AUDITORY SELECTIVE ATTENTION [J].

KNIGHT, RT ;

HILLYARD, SA ;

WOODS, DL ;

NEVILLE, HJ .

ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1981, 52 (06) :571-582

[26]

KNIGHT RT, IN PRESS BRAIN RES

[27]

KNUFFLER SW, 1984, NEURON BRAIN CELLULA, P388

[28] HUMAN AUTONOMY AND THE FRONTAL LOBES .1. IMITATION AND UTILIZATION BEHAVIOR - A NEUROPSYCHOLOGICAL STUDY OF 75 PATIENTS [J].

LHERMITTE, F ;

PILLON, B ;

SERDARU, M .

ANNALS OF NEUROLOGY, 1986, 19 (04) :326-334

[29] HUMAN AUTONOMY AND THE FRONTAL LOBES .2. PATIENT BEHAVIOR IN COMPLEX AND SOCIAL SITUATIONS - THE ENVIRONMENTAL DEPENDENCY SYNDROME [J].

LHERMITTE, F .

ANNALS OF NEUROLOGY, 1986, 19 (04) :335-343

[30] CORTICAL SOMATOSENSORY EVOKED-POTENTIALS IN RESPONSE TO HAND STIMULATION [J].

LUEDERS, H ;

LESSER, RP ;

HAHN, J ;

DINNER, DS ;

KLEM, G .

JOURNAL OF NEUROSURGERY, 1983, 58 (06) :885-894

← 1 2 3 4 5 →