GATING OF SOMATOSENSORY INPUT BY HUMAN PREFRONTAL CORTEX

被引：125

作者：

YAMAGUCHI, S ^{[1
]}

KNIGHT, RT ^{[1
]}

机构：

[1] SHIMANE MED UNIV,DIV INTERNAL MED 3,IZUMO,SHIMANE 693,JAPAN

来源：

BRAIN RESEARCH | 1990年 / 521卷 / 1-2期

关键词：

Gating; Inhibition; Prefrontal cortex; Somatosensory evoked potential;

D O I：

10.1016/0006-8993(90)91553-S

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Somatosensory evoked potentials (SEPs) to median nerve stimulation were recorded in controls and in patients with focal lesions in dorsolateral prefrontal cortex (PFCx). Unilateral PFCx lesions increased the amplitude of the P26 component generated in postcentral areas 1 and 2. The amplitudes of the N28, P45 and N67 SEP components recorded over post-rolandic and frontal electrodes were also enhanced by PFCx damage. In contrast, the N19 component generated in postcentral area 3b was unaffected by PFCx lesions. The results indicate that PFCx exerts inhibitory modulation on sensory processing that may be mediated by corticocortical PFCx-parietal connections. © 1990.

引用

页码：281 / 288

页数：8

共 47 条

[31]

Luria Aleksandr Romanovich, 2012, HIGHER CORTICAL FUNC

[32] ASTEREOGNOSIS AND DISSOCIATED LOSS OF FRONTAL OR PARIETAL COMPONENTS OF SOMATOSENSORY EVOKED-POTENTIALS IN HEMISPHERIC LESIONS - DETAILED CORRELATIONS WITH CLINICAL SIGNS AND COMPUTERIZED TOMOGRAPHIC SCANNING [J].

MAUGUIERE, F ;

DESMEDT, JE ;

COURJON, J .

BRAIN, 1983, 106 (JUN) :271-311

[33] EFFECTS OF DIFFERENT BRAIN LESIONS ON CARD SORTING - ROLE OF FRONTAL LOBES [J].

MILNER, B .

ARCHIVES OF NEUROLOGY, 1963, 9 (01) :90-&

[34]

MILNER B, 1982, NEUROPSYCHOLOGY COGN, P221

[35] SOMATOSENSORY EVOKED-POTENTIALS - ABNORMALITIES WITH FOCAL BRAIN-LESIONS REMOTE FROM THE PRIMARY SENSORIMOTOR AREA [J].

OBESO, JA ;

MARTIMASSO, JF ;

CARRERA, N .

ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1980, 49 (1-2) :59-65

[36]

Pandya DN., 1987, FRONTAL LOBES REVISI

[37] THE UTILITY OF THE WISCONSIN CARD SORTING TEST IN DETECTING AND LOCALIZING FRONTAL-LOBE LESIONS [J].

ROBINSON, AL ;

HEATON, RK ;

LEHMAN, RAW ;

STILSON, DW .

JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY, 1980, 48 (05) :605-614

[38]

SKINNER JE, 1977, PROGR CLIN NEUROPHYS, V1, P30

[39]

Stuss D.T., 1986, FRONTAL LOBES

[40] THE MAGNETIC AND ELECTRIC-FIELDS AGREE WITH INTRACRANIAL LOCALIZATIONS OF SOMATOSENSORY CORTEX [J].

SUTHERLING, WW ;

CRANDALL, PH ;

DARCEY, TM ;

BECKER, DP ;

LEVESQUE, MF ;

BARTH, DS .

NEUROLOGY, 1988, 38 (11) :1705-1714

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