GAMMA-DELTA T-CELL DEVELOPMENT

被引：54

作者：

ALLISON, JP

机构：

[1] University of California, Berkeley

来源：

CURRENT OPINION IN IMMUNOLOGY | 1993年 / 5卷 / 02期

关键词：

D O I：

10.1016/0952-7915(93)90011-G

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Gammadelta T cells consist of multiple lineages of cells with distinct antigen receptor repertoires, tissue localization and function. Recent evidence suggests that the ordered appearance of these sublineages during development is a result of programed rearrangement of V(gamma)-gene segments. It appears that the T-cell receptor repertoire, at least of the gamma(delta) T cells with invariant receptors, is the result of site-directed rearrangement and cellular selection does not play a major role.

引用

页码：241 / 246

页数：6

共 41 条

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