PIGMENTED VILLONODULAR SYNOVITIS - MONOCLONALITY AND METASTASIS - A CASE FOR NEOPLASTIC ORIGIN

被引：81

作者：

CHOONG, PFM

WILLEN, H

NILBERT, M

MERTENS, F

MANDAHL, N

CARLEN, B

RYDHOLM, A

机构：

[1] UNIV LUND HOSP,DEPT ORTHOPED,S-22185 LUND,SWEDEN

[2] UNIV LUND HOSP,DEPT PATHOL & CYTOL,S-22185 LUND,SWEDEN

[3] UNIV LUND HOSP,DEPT CLIN GENET,S-22185 LUND,SWEDEN

来源：

ACTA ORTHOPAEDICA SCANDINAVICA | 1995年 / 66卷 / 01期

关键词：

D O I：

10.3109/17453679508994643

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

We report a 48-year follow-up of a case of recurrent pigmented villonodular synovitis of the knee. Subcutaneous metastasis to the contralateral thigh was an unusual finding. Histology demonstrated fibroblastic and histiocytic proliferation, as well as increased mitotic activity in recurrent lesions. Cytogenetic analyses demonstrated monoclonality and chromosomal abnormalities. Our findings support a neoplastic origin of this lesion.

引用

页码：64 / 68

页数：5

共 15 条

[1]

FIALKOW PJ, 1971, ADV CANCER RES, V15, P191

[2] TRISOMY-5 AND TRISOMY-7 ARE NONRANDOM ABERRATIONS IN PIGMENTED VILLONODULAR SYNOVITIS - CONFIRMATION OF TRISOMY-7 IN UNCULTURED CELLS [J].