LABORATORY AND CLINICAL ASPECTS OF INHERITED THROMBOTIC DISORDERS

被引：19

作者：

RODGERS, GM

CHANDLER, WL

机构：

[1] UNIV UTAH, MED CTR, DEPT PATHOL, SALT LAKE CITY, UT 84132 USA

[2] VET ADM MED CTR, SALT LAKE CITY, UT 84148 USA

[3] UNIV WASHINGTON, DEPT LAB MED, SEATTLE, WA 98195 USA

来源：

AMERICAN JOURNAL OF HEMATOLOGY | 1992年 / 41卷 / 02期

关键词：

ANTITHROMBIN-III; PROTEIN-C; PROTEIN-S; FIBRINOLYSIS; HOMOCYSTINURIA; DYSFIBRINOGENEMIA;

D O I：

10.1002/ajh.2830410209

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The laboratory evaluation of patients with recurrent thrombosis is frequently frustrating, with a low diagnostic yield obtained despite extensive testing. The likelihood of reaching a diagnosis in these patients can be increased by considering diagnostic possibilities usually overlooked and by using assays optimal for their detection. This review summarizes clinical and laboratory issues important in inherited thrombotic disease and discusses practical aspects and a strategy for laboratory testing. New information is provided on the fibrinolytic disorders that may be a common cause of recurrent thrombosis.

引用

页码：113 / 122

页数：10

共 63 条

[21] TREATMENT OF HOMOZYGOUS PROTEIN-C DEFICIENCY AND NEONATAL PURPURA FULMINANS WITH A PURIFIED PROTEIN-C CONCENTRATE [J].