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PROTEOLYTIC DEGRADATION OF HETEROLOGOUS PROTEINS EXPRESSED IN ASPERGILLUS-NIGER

被引：57
作者：
ARCHER, DB
MACKENZIE, DA
JEENES, DJ
ROBERTS, IN
机构：
[1] AFRC Institute of Food Research, Norwich, NR4 7UA, Norwich Research Park, Colney
来源：
BIOTECHNOLOGY LETTERS | 1992年 / 14卷 / 05期
关键词：
D O I：
10.1007/BF01021247
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Proteolytic degradation of heterologous proteins expressed in the filamentous fungus Aspergillus niger reduces the yield of authentic target protein. The activities of A. niger proteases are differentiated by their effects on two proteins expressed and secreted from A. niger: hen ego-white lysozyme and porcine pancreatic phospholipase A2.
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页码：357 / 362
页数：6
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