STUDIES ON MECHANISM OF ACTION OF GOUGEROTIN .3. ENHANCEMENT OF ENZYMATIC BINDING OF PHENYLALANYL-TRNA TO RIBOSOMES BY GOUGEROTIN

被引：12

作者：

YUKIOKA, M

MORISAWA, S

机构：

[1] Department of Biochemistry, Osaka City University Medical School, Abeno-ku, Osaka

来源：

JOURNAL OF BIOCHEMISTRY | 1969年 / 66卷 / 02期

关键词：

D O I：

10.1093/oxfordjournals.jbchem.a129140

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Gougerotin, together with blasticidin S and puromycin, enhanced the T factor-dependent enzymatic binding of phenylalanyl-tRNA to ribosomes. But, they have no effect on the nonenzymatic binding of phenylalanyl-tRNA to ribosomes or on the GTP binding activity of T factor.This gougerotin-dependent stimulation of the enzymatic binding of phenylalanyl-tRNA to ribosomes seems to be responsible for the increment of the number of poly-phenylalanine peptides produced in the presence of gougerotin. © 1969 BY THE JOURNAL OF BIOCHEMISTRY.

引用

页码：241 / &

共 20 条

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