ANIMAL BIOAVAILABILITY OF DEFINED XENOBIOTIC LIGNIN METABOLITES

被引：26

作者：

SANDERMANN, H ^{[1
]}

ARJMAND, M ^{[1
]}

GENNITY, I ^{[1
]}

WINKLER, R ^{[1
]}

STRUBLE, CB ^{[1
]}

ASCHBACHER, PW ^{[1
]}

机构：

[1] USDA,RED RIVER VALLEY AGR RES CTR,FARGO,ND 58105

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 1990年 / 38卷 / 09期

关键词：

D O I：

10.1021/jf00099a020

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

Lignin has been recognized as a major component of bound pesticide residues in plants and is thought to be undigestible in animals. Two defined ring-U-14C-labeled chloroaniline/lignin metabolites have now been fed to rats, where a release of ~66% of the bound xenobiotic occurred in the form of simple chloroaniline derivatives. The observed high degree of bioavailability indicates that bound pesticidal residues may possess ecotoxicological significance. In parallel studies, the white-rot fungus Phanerochaete chrysosporium was more efficient, and a soil system was much less efficient, in the degradation of the [ring-U-14C]chloroaniline/lignin metabolites. © 1990, American Chemical Society. All rights reserved.

引用

页码：1877 / 1880

页数：4

共 27 条

[11]

HARVEY J, 1983, PESTICIDE CHEM HUMAN, V3, P369

[12]

HUBER R, 1983, PESTICIDE CHEM HUMAN, V3, P357

[13]

KAO J, 1978, DRUG METAB DISPOS, V6, P549

[14]

Khan S. U., 1987, Pesticide science and biotechnology. Proceedings of the 6th international congress of pesticide chemistry, held in Ottawa, Canada, 10-15 August 1986., P417

[15]

KOVACS MF, 1986, RESIDUE REV, V97, P1

[16] STUDIES IN DETOXICATION .84. METABOLISM OF [C-14]ANILINE IN THE RABBIT AND OTHER ANIMALS [J].