Prion diseases

被引：19

作者：

Collinge, John ^{[1
]}

Palmer, Mark S. ^{[1
]}

机构：

[1] St Marys Hosp, Med Sch, Dept Biochem & Mol Genet, London W2 1PG, England

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1992年 / 2卷 / 03期

关键词：

D O I：

10.1016/S0959-437X(05)80156-X

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

There have been remarkably rapid advances in the understanding of prion diseases over the past year. The controversial notion that the transmissible agent may be an abnormal isoform of a host-encoded protein, the prion protein, is now gaining wide acceptance. The conundrum of how a disease can both be inherited as an autosomal dominant condition and also be experimentally transmissible by inoculation is beginning to make sense.

引用

页码：448 / 454

页数：7

共 36 条

[1] AMINO-ACID POLYMORPHISM IN HUMAN PRION PROTEIN AND AGE AT DEATH IN INHERITED PRION DISEASE
BAKER, HF
POULTER, M
CROW, TJ
FRITH, CD
LOFTHOUSE, R
RIDLEY, RM
COLLINGE, J
[J]. LANCET, 1991, 337 (8752) : 1286 - 1286
[2] SCRAPIE AND CELLULAR PRION PROTEINS DIFFER IN THEIR KINETICS OF SYNTHESIS AND TOPOLOGY IN CULTURED-CELLS
BORCHELT, DR
SCOTT, M
TARABOULOS, A
STAHL, N
PRUSINER, SB
[J]. JOURNAL OF CELL BIOLOGY, 1990, 110 (03) : 743 - 752
[3] THE EPIDEMIOLOGY OF CREUTZFELDT-JAKOB DISEASE - CONCLUSION OF A 15-YEAR INVESTIGATION IN FRANCE AND REVIEW OF THE WORLD LITERATURE
BROWN, P
CATHALA, F
RAUBERTAS, RF
GAJDUSEK, DC
CASTAIGNE, P
[J]. NEUROLOGY, 1987, 37 (06) : 895 - 904
[4] MORTALITY, NEOPLASIA, AND CREUTZFELDT-JAKOB DISEASE IN PATIENTS TREATED WITH HUMAN PITUITARY GROWTH-HORMONE IN THE UNITED-KINGDOM
BUCHANAN, CR
PREECE, MA
MILNER, RDG
[J]. BRITISH MEDICAL JOURNAL, 1991, 302 (6780) : 824 - 828
[5] CAUGHEY B, 1991, J BIOL CHEM, V266, P18217
[6] NORMAL AND SCRAPIE-ASSOCIATED FORMS OF PRION PROTEIN DIFFER IN THEIR SENSITIVITIES TO PHOSPHOLIPASE AND PROTEASES IN INTACT NEUROBLASTOMA-CELLS
CAUGHEY, B
NEARY, K
BULLER, R
ERNST, D
PERRY, LL
CHESEBRO, B
RACE, RE
[J]. JOURNAL OF VIROLOGY, 1990, 64 (03) : 1093 - 1101
[7] COLLINGE J, 1991, AM J HUM GENET, V49, P1351
[8] GENETIC PREDISPOSITION TO IATROGENIC CREUTZFELDT-JAKOB DISEASE
COLLINGE, J
PALMER, MS
DRYDEN, AJ
[J]. LANCET, 1991, 337 (8755) : 1441 - 1442
[9] PRION DEMENTIA WITHOUT CHARACTERISTIC PATHOLOGY
COLLINGE, J
OWEN, F
POULTER, M
LEACH, M
CROW, TJ
ROSSOR, MN
HARDY, J
MULLAN, MJ
JANOTA, I
LANTOS, PL
[J]. LANCET, 1990, 336 (8706) : 7 - 9
[10] COLLINGE J, 1992, BRAIN

← 1 2 3 4 →