ACETOGENINS OF ANNONACEAE .13. A NEW TYPE OF CYTOTOXIC ACETOGENINS - THE TETRAHYDROFURANIC BETA-HYDROXY METHYL GAMMA-LACTONES

被引：34

作者：

CORTES, D ^{[1
]}

MYINT, SH ^{[1
]}

LEBOEUF, M ^{[1
]}

CAVE, A ^{[1
]}

机构：

[1] UNIV PARIS 11, FAC PHARM, PHARMACOGNOSIE LAB, CNRS, SDI 62330, F-92290 CHATENAY MALABRY, FRANCE

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 43期

关键词：

ACETOGENINS; BETA-HYDROXY METHYL GAMMA-LACTONES; CYTOTOXICITY; ANNONA CHERIMOLIA;

D O I：

10.1016/0040-4039(91)80771-W

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new type of cytotoxic Annonaceous acetogenins has been isolated from Annona cherimolia seeds. The structures of two new acetogenins, itrabin (1) and jetein (2), characterized by a saturated beta-hydroxy methyl gamma-lactone moiety with one or two tetrahydrofuran rings, were established on the basis of 2D NMR experiments.

引用

页码：6133 / 6134

页数：2

共 6 条

[1] CHERIMOLIN AND DIHYDROCHERIMOLIN - 2 NEW BIS-TETRAHYDROFURANNIC GAMMA LACTONES POSSESSING AN ANTIMICROBIAL ACTIVITY
CORTES, D
RIOS, JL
VILLAR, A
VALVERDE, S
[J]. TETRAHEDRON LETTERS, 1984, 25 (30) : 3199 - 3202
[2] COROSSOLONE AND COROSSOLINE, 2 NEW CYTOTOXIC MONOTETRAHYDROFURAN GAMMA-LACTONES
CORTES, D
MYINT, SH
LAURENS, A
HOCQUEMILLER, R
LEBOEUF, M
CAVE, A
[J]. CANADIAN JOURNAL OF CHEMISTRY, 1991, 69 (01) : 8 - 11
[3] CORTES D, 1991, IN PRESS HETRAHEDRON
[4] VALIDATION OF THE H-1-NMR CHEMICAL-SHIFT METHOD FOR DETERMINATION OF STEREOCHEMISTRY IN THE BIS(TETRAHYDROFURANYL) MOIETY OF UVARICIN-RELATED ACETOGENINS FROM ANNONACEAE - ROLLINIASTATIN-1 (AND ASIMICIN)
HOYE, TR
ZHUANG, ZP
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1988, 53 (23) : 5578 - 5580
[5] ACETOGENINS, APORPHINOIDS, AND AZAANTHRAQUINONE FROM ANNONA-CHERIMOLIA SEEDS
RIOS, JL
CORTES, D
VALVERDE, S
[J]. PLANTA MEDICA, 1989, (03) : 321 - 323
[6] ANNONACEOUS ACETOGENINS - A REVIEW
RUPPRECHT, JK
HUI, YH
MCLAUGHLIN, JL
[J]. JOURNAL OF NATURAL PRODUCTS, 1990, 53 (02): : 237 - 278

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