EFFECTS OF PERIPHERAL CHEMOSYMPATHECTOMY AND ADRENALECTOMY UPON BLOOD-PRESSURE RESPONSES OF THE RAT TO FOOTSHOCK UNDER VARYING CONDITIONS - EVIDENCE FOR BEHAVIORAL-EFFECTS ON PATTERNING OF SYMPATHETIC NERVOUS-SYSTEM RESPONSES

被引：10

作者：

WILLIAMS, RB ^{[1
]}

EICHELMAN, BS ^{[1
]}

NG, LKY ^{[1
]}

机构：

[1] NIMH,CLIN PSYCHOBIOL LAB,BETHESDA,MD 20014

来源：

PSYCHOPHYSIOLOGY | 1979年 / 16卷 / 02期

关键词：

6‐hydroxydopamine; Adrenalectomy; Blood pressure response; Coping; Shock‐induced fighting; Sympathetic nervous system;

D O I：

10.1111/j.1469-8986.1979.tb01450.x

中图分类号：

B84 [心理学];

学科分类号：

04 ; 0402 ;

摘要：

A significant decrease in blood pressure is observed after shock‐induced fighting in intact rats. In rats treated with intravenous 6‐hydroxydopamine, a drug that selectively destroys peripheral sympathetic nerve endings when given by this route, this blood pressure response is reversed to a significant increase. In contrast, adrenalectomy converts a slight increase in blood pressure after intact rats are shocked alone in the cage into a significant decrease. These alterations in blood pressure response suggest that the sympathetic response to a stressful stimulus is not an all or none response, but, rather, consists of a patterned activation depending upon the behavioral response available. The current physiological findings are consistent with neuroendocrine research in which coping behavior is found associated with a predominant norepinephrine release by the sympathetic nervous system, and stress without available coping responses is associated with release also of epinephrine. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：89 / 93

页数：5

共 23 条

[11] SERUM DOPAMINE-BETA-HYDROXYLASE (DBH) ACTIVITY AND BLOOD-PRESSURE RESPONSE OF RAT STRAINS TO SHOCK-INDUCED FIGHTING [J].

LAMPRECHT, F ;

EICHELMAN, BS ;

WILLIAMS, RB ;

WOOTEN, GF ;

KOPIN, IJ .

PSYCHOSOMATIC MEDICINE, 1974, 36 (04) :298-303

[12]

LINDGREN P, 1959, ACTA PHYSIOL SCAND, V47, P233

[13]

MALING HM, 1971, J PHARMACOL EXP THER, V176, P672

[14] A REVIEW OF PSYCHOENDOCRINE RESEARCH ON SYMPATHETIC-ADRENAL MEDULLARY SYSTEM [J].

MASON, JW .

PSYCHOSOMATIC MEDICINE, 1968, 30 (5P2) :631-+

[15] PHARMACOLOGICAL MODIFICATIONS OF SYMPATHETIC RESPONSES ELICITED BY HYPOTHALAMIC STIMULATION IN RAT [J].

MORPURGO, C .

BRITISH JOURNAL OF PHARMACOLOGY, 1968, 34 (03) :532-&

[16] ADRENAL TYROSINE HYDROXYLASE - COMPENSATORY INCREASE IN ACTIVITY AFTER CHEMICAL SYMPATHECTOMY [J].

MUELLER, RA ;

THOENEN, H ;

AXELROD, J .

SCIENCE, 1969, 163 (3866) :468-&

[17] CARDIOVASCULAR-BEHAVIORAL INTERACTION - AS IT APPEARS TODAY [J].

OBRIST, PA .

PSYCHOPHYSIOLOGY, 1976, 13 (02) :95-107

[18] PAIN, FEAR, AND ANGER IN HYPERTENSIVES AND NORMOTENSIVES - A PSYCHOPHYSIOLOGICAL STUDY [J].

SCHACHTER, J .

PSYCHOSOMATIC MEDICINE, 1957, 19 (01) :17-29

[19] SOCIAL SETTING - INFLUENCE ON PHYSIOLOGICAL RESPONSE TO ELECTRIC SHOCK IN RAT [J].

WILLIAMS, RB ;

EICHELMAN, B .

SCIENCE, 1971, 174 (4009) :613-+

[20] CARDIOVASCULAR AND NEUROPHYSIOLOGIC CORRELATES OF SENSORY INTAKE AND REJECTION .1. EFFECT OF COGNITIVE TASKS [J].

WILLIAMS, RB ;

BITTKER, TE ;

BUCHSBAUM, MS ;

WYNNE, LC .

PSYCHOPHYSIOLOGY, 1975, 12 (04) :427-433

← 1 2 3 →