QUANTITATIVE STUDY OF MUCOSAL STRUCTURE, ENZYME-ACTIVITIES AND PHENYLALANINE ACCUMULATION IN JEJUNAL BIOPSIES OF PATIENTS WITH EARLY AND LATE ONSET DIABETES

被引：14

作者：

RIECKEN, EO ^{[1
]}

ZENNEK, A ^{[1
]}

LAY, A ^{[1
]}

MENGE, H ^{[1
]}

机构：

[1] UNIV MARBURG, MED KLIN, D-3550 MARBURG, FED REP GER

来源：

GUT | 1979年 / 20卷 / 11期

关键词：

D O I：

10.1136/gut.20.11.1001

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

A study of the three-dimensional structure of the upper jejunal mucosa in diabetics has been carried out. The structural findings were related to 14C-L-phenylalanine uptake in vitro, sucrase activity in mucosal homogenates, and the enzyme content of the absorptive cells as measured cytophotometrically. A low grade mucosal transformation of the sprue-type was found, which was associated with decreased sucrase activity, and with no reduction in phenylalanine accumulation. On the other hand the specific activities of alkaline phosphatase, non-specific esterase, and succinic dehydrogenase in the surface cells remained unchanged.

引用

页码：1001 / 1007

页数：7

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