A REMARKABLE INVERSION IN CONFIGURATION OF THE PRODUCT ALCOHOLS FROM THE ASYMMETRIC REDUCTION OF ORTHO-HYDROXYACETOPHENONES WITH B-CHLORODIISOPINOCAMPHEYLBORANE

被引：28

作者：

RAMACHANDRAN, PV ^{[1
]}

GONG, BQ ^{[1
]}

BROWN, HC ^{[1
]}

机构：

[1] PURDUE UNIV,HC BROWN & RB WETHERILL LABS CHEM,W LAFAYETTE,IN 47907

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 14期

关键词：

D O I：

10.1016/S0040-4039(00)76780-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Asymmetric reduction of o-hydroxyacetophenones with B-chlorodiisopinocampheylborane provides product alcohols with the apposite configuration compared to those produced in the reduction of the corresponding o-methoxyacetophenones. The implications of this result for organic synthesis are discussed.

引用

页码：2141 / 2144

页数：4

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