MOLECULAR-BASIS OF GONADOTROPIN RECEPTOR REGULATION

被引：25

作者：

HSUEH, AJW

LAPOLT, PS

机构：

来源：

TRENDS IN ENDOCRINOLOGY AND METABOLISM | 1992年 / 3卷 / 05期

关键词：

D O I：

10.1016/1043-2760(92)90166-X

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The anterior pituitary hormones, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), act upon the ovary and testis via occupancy of specific cell membrane receptors, resulting in increased cAMP production, steroidogenesis, and expression of differentiation-related genes. Recent cloning of the cDNAs for LH and FSH receptors allows the analysis of mRNA levels for these receptors in gonadal tissues. This review summarizes progress in elucidating the molecular basis of LH and FSH receptor gene regulation in the ovary and testis during different physiologic states.

引用

页码：164 / 170

页数：7

共 43 条

[1] CLONING OF RAT LUTROPIN (LH) RECEPTOR ANALOGS LACKING THE SOYBEAN LECTIN DOMAIN
BERNARD, MP
MYERS, RV
MOYLE, WR
[J]. MOLECULAR AND CELLULAR ENDOCRINOLOGY, 1990, 71 (03) : R19 - R23
[2] AMINO-TERMINAL LEUCINE-RICH REPEATS IN GONADOTROPIN RECEPTORS DETERMINE HORMONE SELECTIVITY
BRAUN, T
SCHOFIELD, PR
SPRENGEL, R
[J]. EMBO JOURNAL, 1991, 10 (07) : 1885 - 1890
[3] RECOMBINANT FOLLICLE-STIMULATING-HORMONE INDUCES OVULATION AND TISSUE PLASMINOGEN-ACTIVATOR EXPRESSION IN HYPOPHYSECTOMIZED RATS
GALWAY, AB
LAPOLT, PS
TSAFRIRI, A
DARGAN, CM
BOIME, I
HSUEH, AJW
[J]. ENDOCRINOLOGY, 1990, 127 (06) : 3023 - 3028
[4] COMPOSITE STRUCTURE OF THE HUMAN THYROTROPIN RECEPTOR GENE
GROSS, B
MISRAHI, M
SAR, S
MILGROM, E
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1991, 177 (02) : 679 - 687
[5] GUDERMANN T, 1992, J BIOL CHEM, V259, P15028
[6] EXPRESSION OF FOLLICLE-STIMULATING-HORMONE RECEPTOR MESSENGER-RNA IN RAT TESTES AND SERTOLI CELLS
HECKERT, LL
GRISWOLD, MD
[J]. MOLECULAR ENDOCRINOLOGY, 1991, 5 (05) : 670 - 677
[7] CHANGES IN CONTENT OF CYTOCHROME P45017-ALPHA, CYTOCHROME P450SCC, AND 3-HYDROXY-3-METHYLGLUTARYL COA REDUCTASE IN DEVELOPING RAT OVARIAN FOLLICLES AND CORPORA-LUTEA - CORRELATION WITH THECA CELL STEROIDOGENESIS
HEDIN, L
RODGERS, RJ
SIMPSON, ER
RICHARDS, JS
[J]. BIOLOGY OF REPRODUCTION, 1987, 37 (01) : 211 - 223
[8] EVIDENCE THAT HUMAN CHORIONIC-GONADOTROPIN LUTEINIZING-HORMONE RECEPTOR DOWN-REGULATION INVOLVES DECREASED LEVELS OF RECEPTOR MESSENGER-RIBONUCLEIC-ACID
HOFFMAN, YM
PEEGEL, H
SPROCK, MJE
ZHANG, QY
MENON, KMJ
[J]. ENDOCRINOLOGY, 1991, 128 (01) : 388 - 393
[9] GONADOTROPIN-INDUCED REGULATION OF LUTEINIZING-HORMONE RECEPTORS AND DESENSITIZATION OF TESTICULAR 3'-5'-CYCLIC AMP AND TESTOSTERONE RESPONSES
HSUEH, AJW
DUFAU, ML
CATT, KJ
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (02) : 592 - 595
[10] JAASKELAINEN K, 1983, ACTA ENDOCRINOL-COP, V103, P406

← 1 2 3 4 5 →