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MOLECULAR-BASIS OF GONADOTROPIN RECEPTOR REGULATION

被引：25
作者：
HSUEH, AJW
LAPOLT, PS
机构：
来源：
TRENDS IN ENDOCRINOLOGY AND METABOLISM | 1992年 / 3卷 / 05期
关键词：
D O I：
10.1016/1043-2760(92)90166-X
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The anterior pituitary hormones, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), act upon the ovary and testis via occupancy of specific cell membrane receptors, resulting in increased cAMP production, steroidogenesis, and expression of differentiation-related genes. Recent cloning of the cDNAs for LH and FSH receptors allows the analysis of mRNA levels for these receptors in gonadal tissues. This review summarizes progress in elucidating the molecular basis of LH and FSH receptor gene regulation in the ovary and testis during different physiologic states.
引用
收藏
页码：164 / 170
页数：7
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