学术探索
学术期刊
新闻热点
数据分析
智能评审
立即登录
MYOBLASTS FROM FETAL AND ADULT SKELETAL-MUSCLE REGULATE MYOSIN EXPRESSION DIFFERENTLY
被引:42
作者
:
HARTLEY, RS
论文数:
0
引用数:
0
h-index:
0
机构:
UNIV CALIF DAVIS,DEPT FOOD SCI & TECHNOL,DAVIS,CA 95616
UNIV CALIF DAVIS,DEPT FOOD SCI & TECHNOL,DAVIS,CA 95616
HARTLEY, RS
[
1
]
BANDMAN, E
论文数:
0
引用数:
0
h-index:
0
机构:
UNIV CALIF DAVIS,DEPT FOOD SCI & TECHNOL,DAVIS,CA 95616
UNIV CALIF DAVIS,DEPT FOOD SCI & TECHNOL,DAVIS,CA 95616
BANDMAN, E
[
1
]
YABLONKAREUVENI, Z
论文数:
0
引用数:
0
h-index:
0
机构:
UNIV CALIF DAVIS,DEPT FOOD SCI & TECHNOL,DAVIS,CA 95616
UNIV CALIF DAVIS,DEPT FOOD SCI & TECHNOL,DAVIS,CA 95616
YABLONKAREUVENI, Z
[
1
]
机构
:
[1]
UNIV CALIF DAVIS,DEPT FOOD SCI & TECHNOL,DAVIS,CA 95616
来源
:
DEVELOPMENTAL BIOLOGY
|
1991年
/ 148卷
/ 01期
关键词
:
D O I
:
10.1016/0012-1606(91)90334-Y
中图分类号
:
Q [生物科学];
学科分类号
:
07 ;
0710 ;
09 ;
摘要
:
We compared the expression of myosin heavy chains in myogenic cultures prepared from fetal (embryonic Day 10) and adult (12-16 week) chicken pectoralis muscle using immunofluorescence with isoform-specific monoclonal antibodies. We found that the majority of fetal myocytes (differentiated myoblasts) and myotubes coexpressed ventricular and embryonic myosin heavy chains in culture. Also, when fetal cells were plated at a clonal density most clones coexpressed both ventricular and embryonic isoforms. In contrast, all adult myocytes and newly formed adult myotubes expressed just ventricular myosin, whether plated at mass or clonal densities. Within 12-24 hr of the onset of fusion, adult myotubes began to express embryonic myosin as well. Eventually, the majority of adult myotubes coexpressed both ventricular and embryonic myosin. The delay of embryonic myosin expression until after fusion was also seen in passaged adult myoblasts and in myoblasts isolated from regenerating adult muscle. The expression of embryonic myosin can be abolished by inhibiting fusion with EGTA in adult but not in fetal cultures. We conclude that both fetal and adult myotubes express ventricular and embryonic myosins but only fetal myocytes express the embryonic isoform prior to fusion. This difference in the regulation of embryonic myosin expression between fetal and adult myoblasts supports the hypothesis that these cells may represent two distinct populations of myogenic precursors. © 1991.
引用
收藏
页码:249 / 260
页数:12
相关论文
共 46 条
[41]
ISOLATION AND CLONAL ANALYSIS OF SATELLITE CELLS FROM CHICKEN PECTORALIS-MUSCLE
YABLONKAREUVENI, Z
论文数:
0
引用数:
0
h-index:
0
YABLONKAREUVENI, Z
QUINN, LS
论文数:
0
引用数:
0
h-index:
0
QUINN, LS
NAMEROFF, M
论文数:
0
引用数:
0
h-index:
0
NAMEROFF, M
[J].
DEVELOPMENTAL BIOLOGY,
1987,
119
(01)
: 252
-
259
[42]
TEMPORAL DIFFERENCES IN DESMIN EXPRESSION BETWEEN MYOBLASTS FROM EMBRYONIC AND ADULT CHICKEN SKELETAL-MUSCLE
YABLONKAREUVENI, Z
论文数:
0
引用数:
0
h-index:
0
机构:
Department of Biological Structure, School of Medicine, University of Washington, Seattle, Washington
YABLONKAREUVENI, Z
NAMEROFF, M
论文数:
0
引用数:
0
h-index:
0
机构:
Department of Biological Structure, School of Medicine, University of Washington, Seattle, Washington
NAMEROFF, M
[J].
DIFFERENTIATION,
1990,
45
(01)
: 21
-
28
[43]
YABLONKAREUVENI Z, 1988, CELL TISSUE RES, V252, P339
[44]
YABLONKAREUVENI Z, 1988, J CELL BIOCHEM S, V12, P334
[45]
MYOSIN HEAVY-CHAIN EXPRESSION IN EMBRYONIC CARDIAC CELL-CULTURES
ZADEH, BJ
论文数:
0
引用数:
0
h-index:
0
机构:
CORNELL UNIV,MED CTR,COLL MED,DEPT SURG,NEW YORK,NY 10021
CORNELL UNIV,MED CTR,COLL MED,DEPT SURG,NEW YORK,NY 10021
ZADEH, BJ
GONZALEZSANCHEZ, A
论文数:
0
引用数:
0
h-index:
0
机构:
CORNELL UNIV,MED CTR,COLL MED,DEPT SURG,NEW YORK,NY 10021
CORNELL UNIV,MED CTR,COLL MED,DEPT SURG,NEW YORK,NY 10021
GONZALEZSANCHEZ, A
FISCHMAN, DA
论文数:
0
引用数:
0
h-index:
0
机构:
CORNELL UNIV,MED CTR,COLL MED,DEPT SURG,NEW YORK,NY 10021
CORNELL UNIV,MED CTR,COLL MED,DEPT SURG,NEW YORK,NY 10021
FISCHMAN, DA
BADER, DM
论文数:
0
引用数:
0
h-index:
0
机构:
CORNELL UNIV,MED CTR,COLL MED,DEPT SURG,NEW YORK,NY 10021
CORNELL UNIV,MED CTR,COLL MED,DEPT SURG,NEW YORK,NY 10021
BADER, DM
[J].
DEVELOPMENTAL BIOLOGY,
1986,
115
(01)
: 204
-
214
[46]
[No title captured]
←
1
2
3
4
5
→
共 46 条
[41]
ISOLATION AND CLONAL ANALYSIS OF SATELLITE CELLS FROM CHICKEN PECTORALIS-MUSCLE
YABLONKAREUVENI, Z
论文数:
0
引用数:
0
h-index:
0
YABLONKAREUVENI, Z
QUINN, LS
论文数:
0
引用数:
0
h-index:
0
QUINN, LS
NAMEROFF, M
论文数:
0
引用数:
0
h-index:
0
NAMEROFF, M
[J].
DEVELOPMENTAL BIOLOGY,
1987,
119
(01)
: 252
-
259
[42]
TEMPORAL DIFFERENCES IN DESMIN EXPRESSION BETWEEN MYOBLASTS FROM EMBRYONIC AND ADULT CHICKEN SKELETAL-MUSCLE
YABLONKAREUVENI, Z
论文数:
0
引用数:
0
h-index:
0
机构:
Department of Biological Structure, School of Medicine, University of Washington, Seattle, Washington
YABLONKAREUVENI, Z
NAMEROFF, M
论文数:
0
引用数:
0
h-index:
0
机构:
Department of Biological Structure, School of Medicine, University of Washington, Seattle, Washington
NAMEROFF, M
[J].
DIFFERENTIATION,
1990,
45
(01)
: 21
-
28
[43]
YABLONKAREUVENI Z, 1988, CELL TISSUE RES, V252, P339
[44]
YABLONKAREUVENI Z, 1988, J CELL BIOCHEM S, V12, P334
[45]
MYOSIN HEAVY-CHAIN EXPRESSION IN EMBRYONIC CARDIAC CELL-CULTURES
ZADEH, BJ
论文数:
0
引用数:
0
h-index:
0
机构:
CORNELL UNIV,MED CTR,COLL MED,DEPT SURG,NEW YORK,NY 10021
CORNELL UNIV,MED CTR,COLL MED,DEPT SURG,NEW YORK,NY 10021
ZADEH, BJ
GONZALEZSANCHEZ, A
论文数:
0
引用数:
0
h-index:
0
机构:
CORNELL UNIV,MED CTR,COLL MED,DEPT SURG,NEW YORK,NY 10021
CORNELL UNIV,MED CTR,COLL MED,DEPT SURG,NEW YORK,NY 10021
GONZALEZSANCHEZ, A
FISCHMAN, DA
论文数:
0
引用数:
0
h-index:
0
机构:
CORNELL UNIV,MED CTR,COLL MED,DEPT SURG,NEW YORK,NY 10021
CORNELL UNIV,MED CTR,COLL MED,DEPT SURG,NEW YORK,NY 10021
FISCHMAN, DA
BADER, DM
论文数:
0
引用数:
0
h-index:
0
机构:
CORNELL UNIV,MED CTR,COLL MED,DEPT SURG,NEW YORK,NY 10021
CORNELL UNIV,MED CTR,COLL MED,DEPT SURG,NEW YORK,NY 10021
BADER, DM
[J].
DEVELOPMENTAL BIOLOGY,
1986,
115
(01)
: 204
-
214
[46]
[No title captured]
←
1
2
3
4
5
→