USE OF NPE-PROTECTING GROUPS FOR THE PREPARATION OF OLIGONUCLEOTIDES WITHOUT USING NUCLEOPHILES DURING THE FINAL DEPROTECTION

被引：13

作者：

AVINO, AM ^{[1
]}

ERITJA, R ^{[1
]}

机构：

[1] CSIC,CID,DEPT MOLEC GENET,E-08034 BARCELONA,SPAIN

来源：

NUCLEOSIDES & NUCLEOTIDES | 1994年 / 13卷 / 10期

关键词：

D O I：

10.1080/15257779408013207

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The preparation of O-(4-nitrophenyl)ethyl phosphoramidites and H-phosphonate derivatives of Npe protected nucleosides is described together with the use of these products to prepare oligodeoxynucleotides without using nucleophiles during the final deprotection.

引用

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页码：2059 / 2069

页数：11

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