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IMPLICATIONS OF THE SNARE HYPOTHESIS FOR INTRACELLULAR MEMBRANE TOPOLOGY AND DYNAMICS

被引：504
作者：
ROTHMAN, JE [1 ]
WARREN, G [1 ]
机构：
[1] IMPERIAL CANC RES FUND,CELL BIOL LAB,LONDON WC2A 3PX,ENGLAND
来源：
CURRENT BIOLOGY | 1994年 / 4卷 / 03期
关键词：
D O I：
10.1016/S0960-9822(00)00051-8
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The SNARE hypothesis provides a mechanism for the specific docking and fusion of transport vesicles with their target membranes. A simple extension of the hypothesis can explain many cellular processes, including the stacking of Golgi cisternae, retrograde transport and homotypic fusion; it can also explain the morphology of intracellular membranes and their dynamics during mitosis. © 1994 Elsevier Science Ltd. All rights reserved.
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页码：220 / 233
页数：14
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