TRANSFORMATIONS USING BENZYL 6-ISOCYANOPENICILLANATE

被引：16

作者：

BENTLEY, PH ^{[1
]}

CLAYTON, JP ^{[1
]}

BOLES, MO ^{[1
]}

GIRVEN, RJ ^{[1
]}

机构：

[1] PLYMOUTH POLYTECH,SCH MATH SCI,PLYMOUTH PL4 8AA,DEVONSHIRE,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1979年 / 10期

关键词：

D O I：

10.1039/p19790002455

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The preparation and C-6 epimerisation of benzyl 6α- isocyanopenicillanate is described. By utilising the activating influence of the isocyanide group and a subsequent conversion of this group into an amino-group under mild conditions, 6α-substituted penicillins were thereby prepared. Additionally, several novel rearrangements of these isocyanides are described.

引用

页码：2455 / 2467

页数：13

共 33 条

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