THE INHIBITION SITE OF MPP+, THE NEUROTOXIC BIOACTIVATION PRODUCT OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE IS NEAR THE Q-BINDING SITE OF NADH DEHYDROGENASE

被引:97
作者
RAMSAY, RR
KOWAL, AT
JOHNSON, MK
SALACH, JI
SINGER, TP
机构
[1] VET ADM MED CTR,DIV MOLEC BIOL,4150 CLEMENT ST,SAN FRANCISCO,CA 94121
[2] UNIV GEORGIA,DEPT CHEM,ATHENS,GA 30601
[3] UNIV CALIF SAN FRANCISCO,DEPT BIOCHEM & BIOPHYS,SAN FRANCISCO,CA 94143
[4] UNIV CALIF SAN FRANCISCO,DEPT PHARMACEUT CHEM,SAN FRANCISCO,CA 94143
关键词
D O I
10.1016/0003-9861(87)90531-5
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:645 / 649
页数:5
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