A NEW ELECTROPHILIC ALANINOL SYNTHON - A GENERAL-ROUTE TO OXAZOLIDINONES OF D-2-AMINO OR (R)-2-AMINO ALCOHOLS FROM L-SERINE

被引：38

作者：

SIBI, MP

RUTHERFORD, D

SHARMA, R

机构：

[1] Department of Chemistry, North Dakota State University, Fargo

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1994年 / 13期

关键词：

D O I：

10.1039/p19940001675

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new electrophilic alaninol synthon, (S)-4-(4'-tolylsulfonyloxymethyl) oxazolidin-2-one, derived from serine, undergoes nucleophilic displacements with Gilman cuprates and/or Grignard/CuX reagents in high yield to provide (R)-4-substituted oxazolidinones.

引用

页码：1675 / 1678

页数：4

共 58 条

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