BMS-192548, A TETRACYCLIC BINDING INHIBITOR OF NEUROPEPTIDE-Y RECEPTORS, FROM ASPERGILLUS-NIGER WB2346 .2. PHYSICOCHEMICAL PROPERTIES AND STRUCTURAL CHARACTERIZATION

被引:20
作者
SHU, YZ
CUTRONE, JFQ
KLOHR, SE
HUANG, S
机构
[1] Bristol-Myers Squibb Pharmaceutical Research Institute, Wallingford, CT 06492
关键词
D O I
10.7164/antibiotics.48.1060
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The structure of BMS-192548, a tetracyclic binding inhibitor of neuropeptide Y receptors, was established by spectroscopic methods. The compound has an unusul B-C-D ring beta-diketone moiety.
引用
收藏
页码:1060 / 1065
页数:6
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