SYNTHESIS AND ANTIHERPETIC ACTIVITY OF (+/-)-9-[[(Z)-2-(HYDROXYMETHYL)CYCLOPROPYL]METHYL]GUANINE AND RELATED-COMPOUNDS

被引：90

作者：

ASHTON, WT ^{[1
]}

MEURER, LC ^{[1
]}

CANTONE, CL ^{[1
]}

FIELD, AK ^{[1
]}

HANNAH, J ^{[1
]}

KARKAS, JD ^{[1
]}

LIOU, R ^{[1
]}

PATEL, GF ^{[1
]}

PERRY, HC ^{[1
]}

WAGNER, AF ^{[1
]}

WALTON, E ^{[1
]}

TOLMAN, RL ^{[1
]}

机构：

[1] MERCK SHARP & DOHME RES LABS,W POINT,PA 19486

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1988年 / 31卷 / 12期

关键词：

D O I：

10.1021/jm00120a010

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：2304 / 2315

页数：12

共 56 条

[1] ALLAN RD, 1980, J NEUROCHEM, V34, P652, DOI 10.1111/j.1471-4159.1980.tb11193.x
[2] ACTIVATION BY THYMIDINE KINASE AND POTENT ANTIHERPETIC ACTIVITY OF 2'-NOR-2'-DEOXYGUANOSINE (2'NDG)
ASHTON, WT
KARKAS, JD
FIELD, AK
TOLMAN, RL
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1982, 108 (04) : 1716 - 1721
[3] SYNTHESIS AND ANTIHERPETIC ACTIVITY OF (S)-9-[2,3-DIHYDROXY-1-PROPOXY)METHYL]GUANINE, (R)-9-[2,3-DIHYDROXY-1-PROPOXY)METHYL]GUANINE, AND (+/-)-9-[(2,3-DIHYDROXY-1-PROPOXY)METHYL]GUANINE, LINEAR ISOMERS OF 2'-NOR-2'-DEOXYGUANOSINE
ASHTON, WT
CANNING, LF
REYNOLDS, GF
TOLMAN, RL
KARKAS, JD
LIOU, R
DAVIES, MEM
DEWITT, CM
PERRY, HC
FIELD, AK
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1985, 28 (07) : 926 - 933
[4] BALDWIN JE, 1971, CHEM IND-LONDON, P930
[5] MODIFICATIONS ON THE HETEROCYCLIC BASE OF ACYCLOVIR - SYNTHESES AND ANTIVIRAL PROPERTIES
BEAUCHAMP, LM
DOLMATCH, BL
SCHAEFFER, HJ
COLLINS, P
BAUER, DJ
KELLER, PM
FYFE, JA
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1985, 28 (08) : 982 - 987
[6] CONFORMATIONAL FEATURES OF ACYCLONUCLEOSIDES - STRUCTURE OF ACYCLOVIR, AN ANTIHERPES AGENT
BIRNBAUM, GI
CYGLER, M
SHUGAR, D
[J]. CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1984, 62 (12): : 2646 - 2652
[7] BIRON KK, 1984, HERPESVIRUS, P677
[8] SYNTHESIS OF CYCLOPROPANE DERIVATIVES - PRECURSORS FOR DIMETHYLENECYCLOPROPANE AND TRIMETHYLENECYCLOPROPANE
BLOMQUIST, AT
LONGONE, DT
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1959, 81 (08) : 2012 - 2017
[9] ANTIHERPESVIRUS ACTIVITY OF 9-(4-HYDROXY-3-HYDROXYMETHYLBUT-1-YL)GUANINE (BRL-39123) IN CELL-CULTURE
BOYD, MR
BACON, TH
SUTTON, D
COLE, M
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1987, 31 (08) : 1238 - 1242
[10] THE METHYLATION OF ADENOSINE AND ADENYLIC ACID
BROOKES, P
LAWLEY, PD
[J]. JOURNAL OF THE CHEMICAL SOCIETY, 1960, (FEB): : 539 - 545

← 1 2 3 4 5 6 →