AN IMPROVED STRATEGY FOR THE STEREOSELECTIVE SYNTHESIS OF GLYCOSIDES USING GLYCOSIDASES AS CATALYSTS

被引：13

作者：

BAKER, A ^{[1
]}

TURNER, NJ ^{[1
]}

WEBBERLEY, MC ^{[1
]}

机构：

[1] UNIV EXETER,DEPT CHEM,EXETER EX4 4QD,DEVON,ENGLAND

来源：

TETRAHEDRON-ASYMMETRY | 1994年 / 5卷 / 12期

关键词：

D O I：

10.1016/S0957-4166(00)80398-5

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A alternative strategy for the synthesis of glycosides, using glycosidase enzymes, has been developed. In contrast to previous procedures, this new method uses limiting amounts of the acceptor alcohol substrate in combination with an excess of the glycosyl donor. Using this procedure, a series of mono- and disaccharides have been prepared.

引用

页码：2517 / 2522

页数：6

共 16 条

[1] ENZYMATIC-SYNTHESIS OF DISACCHARIDE-SERINE AND PEPTIDE CONJUGATES
BAY, S
NAMANE, A
CANTACUZENE, D
[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1993, 3 (12) : 2515 - 2520
[2] BJORKLING F, 1988, TETRAHEDRON, V44, P2957
[3] ENZYMATIC-SYNTHESIS OF GLYCOSIDES USING THE BETA-GALACTOSIDASE OF ESCHERICHIA-COLI - REGIOCHEMICAL AND STEREOCHEMICAL STUDIES
CROUT, DHG
MACMANUS, DA
CRITCHLEY, P
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1990, (07): : 1865 - 1868
[4] CHEMOENZYMATIC SYNTHESIS OF A LIPID-LINKED CORE TRISACCHARIDE OF N-LINKED GLYCOPROTEINS
FLITSCH, SL
PINCHES, HL
TAYLOR, JP
TURNER, NJ
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1992, (16): : 2087 - 2093
[5] CHEMOENZYMATIC SYNTHESIS OF A BETA-MANNOSYL-CONTAINING TRISACCHARIDE
FLITSCH, SL
TAYLOR, JP
TURNER, NJ
[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1991, (06) : 382 - 384
[6] SYNTHESIS OF A NOVEL ACCEPTOR SUBSTRATE FOR A MANNOSYL TRANSFERASE
FLITSCH, SL
TAYLOR, JP
TURNER, NJ
[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1991, (06) : 380 - 382
[7] GAIS HJ, TETRAHEDRON LETT, V29, P5743
[8] A NEW MULTIENZYME SYSTEM FOR A ONE-POT SYNTHESIS OF SIALYL OLIGOSACCHARIDES - COMBINED USE OF BETA-GALACTOSIDASE AND ALPHA(2,6)-SIALYLTRANSFERASE COUPLED WITH REGENERATION INSITU OF CMP-SIALIC ACID
HERRMANN, GF
ICHIKAWA, Y
WANDREY, C
GAETA, FCA
PAULSON, JC
WONG, CH
[J]. TETRAHEDRON LETTERS, 1993, 34 (19) : 3091 - 3094
[9] GALACTOSYLATION AND GLUCOSYLATION BY USE OF BETA-GALACTOSIDASE
SAUERBREI, B
THIEM, J
[J]. TETRAHEDRON LETTERS, 1992, 33 (02) : 201 - 204
[10] SCHMIDT RR, 1991, COMPREHENSIVE ORGANI, V6, P33

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