THE RENEWED POTENTIAL FOR FOLATE ANTAGONISTS IN CONTEMPORARY CANCER-CHEMOTHERAPY

被引：169

作者：

BERMAN, EM ^{[1
]}

WERBEL, LM ^{[1
]}

机构：

[1] PARKE DAVIS & CO, DIV PHARMACEUT RES, 2800 PLYMOUTH RD, ANN ARBOR, MI 48105 USA

来源：

关键词：

D O I：

10.1021/jm00106a001

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：479 / 485

页数：7

共 95 条

[61] CLINICAL USE OF RECOMBINANT HUMAN HEMATOPOIETIC GROWTH-FACTORS
LAVER, J
MOORE, MAS
[J]. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1989, 81 (18): : 1370 - 1382
[62] TRIMETREXATE - A 2ND GENERATION FOLATE ANTAGONIST IN CLINICAL-TRIAL
LIN, JT
BERTINO, JR
[J]. JOURNAL OF CLINICAL ONCOLOGY, 1987, 5 (12) : 2032 - 2040
[63] MAROUN J, 1988, SEMIN ONCOL, V15, P17
[64] QUINAZOLINE ANTIFOLATE THYMIDYLATE SYNTHASE INHIBITORS - NITROGEN, OXYGEN, SULFUR, AND CHLORINE SUBSTITUENTS IN THE C2 POSITION
MARSHAM, PR
CHAMBERS, P
HAYTER, AJ
HUGHES, LR
JACKMAN, AL
OCONNOR, BM
BISHOP, JAM
CALVERT, AH
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1989, 32 (03) : 569 - 575
[65] POTENT INHIBITION OF THYMIDYLATE SYNTHASE BY 2 SERIES OF NONCLASSICAL QUINAZOLINES
MCNAMARA, DJ
BERMAN, EM
FRY, DW
WERBEL, LM
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1990, 33 (07) : 2045 - 2051
[66] MORAN RG, 1989, J BIOL CHEM, V264, P21047
[67] FOLATE ANALOGS .24. SYNTHESES OF THE ANTITUMOR AGENTS 10-DEAZAAMINOPTERIN (10-DAAM) AND 10-ETHYL-10-DEAZAAMINOPTERIN (10-EDAAM)
NAIR, MG
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1985, 50 (11) : 1879 - 1884
[68] NOGAE I, 1989, BIOCHEM PHARMACOL, V38, P519
[69] ODWYER PJ, 1985, INVEST NEW DRUG, V3, P71
[70] Palmer D C, 1988, Prog Med Chem, V25, P85, DOI 10.1016/S0079-6468(08)70278-9