ADDITION OF FUNCTIONALIZED ZINC COPPER REAGENTS TO ACETYLENIC ESTERS - SYNTHESIS OF 2-CARBOALKOXY CYCLOHEXENONES

被引:9
作者
CRIMMINS, MT
HUANG, SJ
GUISE, LE
LACY, DB
机构
[1] Venable and Kenan Laboratories, Chemistry University of North Carolina at Chapel Hill, Chapel Hill
关键词
FUNCTIONALIZED ZINC REAGENTS; CARBOALKOXYCYCLOHEXENONES; HOMOENOLATES;
D O I
10.1016/0040-4039(95)01485-Z
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Conjugate addition of the zinc-copper reagent derived from ethyl 4-iodobutyrate to acetylenic esters in the presence of TMSCI and HMPA results in cyclization and formation of 3-alkyl-2-carboalkoxycyclohexenones in good yields.
引用
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页码:7061 / 7064
页数:4
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