INVESTIGATIONS ON THE REACTION OF AMINO-ACIDS WITH ALPHA-DICARBONYL COMPOUNDS .2. VOLATILE PRODUCTS OF THE REACTION OF AMINO-ACIDS WITH DIACETYL (2.3-BUTANEDIONE)

Glycine, α-alanine, β-alanine, phenylalanine, glycylalanine and NH3 were reacted with diacetyl in an aqueous medium. In addition to several nitrogen free compounds some nitrogenous heterocyclic products belonging to the classes of oxazoles, pyrazines, pyrroles and pyridines could be identified. The pyridine derivatives have not previously been described in the literature. Spectral data are given and possible formation mechanisms discussed. © 1979 Springer-Verlag.