THE GENETIC-ENGINEERING OF MONOCLONAL-ANTIBODIES

被引：51

作者：

OWENS, RJ ^{[1
]}

YOUNG, RJ ^{[1
]}

机构：

[1] KINGS COLL,RANDALL INST,LONDON,ENGLAND

来源：

JOURNAL OF IMMUNOLOGICAL METHODS | 1994年 / 168卷 / 02期

关键词：

D O I：

10.1016/0022-1759(94)90051-5

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：149 / 165

页数：17

共 109 条

[21] POLYMERIC IMMUNOGLOBULIN-M IS SECRETED BY TRANSFECTANTS OF NONLYMPHOID CELLS IN THE ABSENCE OF IMMUNOGLOBULIN-J CHAIN [J].

CATTANEO, A ;

NEUBERGER, MS .

EMBO JOURNAL, 1987, 6 (09) :2753-2758

[22] IDENTIFICATION OF THE FC-GAMMA RECEPTOR CLASS-I BINDING-SITE IN HUMAN-IGG THROUGH THE USE OF RECOMBINANT IGG1/IGG2 HYBRID AND POINT-MUTATED ANTIBODIES [J].

CHAPPEL, MS ;

ISENMAN, DE ;

EVERETT, M ;

XU, YY ;

DORRINGTON, KJ ;

KLEIN, MH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (20) :9036-9040

[23]

CHATENOUD L, 1986, J IMMUNOL, V137, P830

[24] A RAPID METHOD OF CLONING FUNCTIONAL VARIABLE-REGION ANTIBODY GENES IN ESCHERICHIA-COLI AS SINGLE-CHAIN IMMUNOTOXINS [J].

CHAUDHARY, VK ;

BATRA, JK ;

GALLO, MG ;

WILLINGHAM, MC ;

FITZGERALD, DJ ;

PASTAN, I .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (03) :1066-1070

[25] CANONICAL STRUCTURES FOR THE HYPERVARIABLE REGIONS OF IMMUNOGLOBULINS [J].

CHOTHIA, C ;

LESK, AM .

JOURNAL OF MOLECULAR BIOLOGY, 1987, 196 (04) :901-917

[26] DOMAIN ASSOCIATION IN IMMUNOGLOBULIN MOLECULES - THE PACKING OF VARIABLE DOMAINS [J].

CHOTHIA, C ;

NOVOTNY, J ;

BRUCCOLERI, R ;

KARPLUS, M .

JOURNAL OF MOLECULAR BIOLOGY, 1985, 186 (03) :651-663

[27]

CLARKSON T, 1991, NATURE, V353, P624

[28] HUMANIZED ANTIBODIES FOR ANTIVIRAL THERAPY [J].

CO, MS ;

DESCHAMPS, M ;

WHITLEY, RJ ;

QUEEN, C .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (07) :2869-2873

[29] THE USE OF ENGINEERED E1A GENES TO TRANSACTIVATE THE HCMV-MIE PROMOTER IN PERMANENT CHO CELL-LINES [J].

COCKETT, MI ;

BEBBINGTON, CR ;

YARRANTON, GT .

NUCLEIC ACIDS RESEARCH, 1991, 19 (02) :319-325

[30] HIGH-LEVEL EXPRESSION OF TISSUE INHIBITOR OF METALLOPROTEINASES IN CHINESE HAMSTER OVARY CELLS USING GLUTAMINE-SYNTHETASE GENE AMPLIFICATION [J].

COCKETT, MI ;

BEBBINGTON, CR ;

YARRANTON, GT .

BIO-TECHNOLOGY, 1990, 8 (07) :662-667

← 1 2 3 4 5 6 7 8 9 10 →