BIOSYNTHESIS OF VITAMIN-B12 - THE STRUCTURE OF FACTOR-IV, THE OXIDIZED FORM OF PRECORRIN-4

被引：31

作者：

THIBAUT, D ^{[1
]}

DEBUSSCHE, L ^{[1
]}

FRECHET, D ^{[1
]}

HERMAN, F ^{[1
]}

VUILHORGNE, M ^{[1
]}

BLANCHE, F ^{[1
]}

机构：

[1] RHONE POULENC RORER SA,CTR RECH VITRY ALFORTVILLE,DEPT ANAL,13 QUAI JULES GUESDE,BP14,F-94403 VITRY,FRANCE

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1993年 / 06期

关键词：

D O I：

10.1039/c39930000513

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

C-13 Labelling and NMR experiments establish the structure of factor IV, the oxidized form of the tetramethylated intermediate on the biosynthetic pathway to precorrin-6x 2 in Pseudomonas denitrificans, thus demonstrating that the contraction of the macrocycle leads to an acetyl derivative at C-1.

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页码：513 / 515

页数：3

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