DIOLS AS SUBSTRATES IN LIPASE-CATALYZED ENANTIOSELECTIVE ACYLATIONS - A BRIEF REVIEW

被引：29

作者：

THEIL, F

机构：

[1] Institut für Angewandte Chemie Berlin-Adlershof, D-12484 Berlin

来源：

CATALYSIS TODAY | 1994年 / 22卷 / 03期

关键词：

D O I：

10.1016/0920-5861(94)80121-5

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

An overview on lipase-catalyzed enantioselective acylations of diols in organic solvents is presented. The application of this biocatalytic process on diols as a special type of bifunctional compounds as substrates is directed on the synthesis of enantiomerically pure building blocks. Prochiral acyclic and cyclic diols can be successfully made asymmetric by using different types of lipases and acylating agents. The kinetic resolution of racemic cyclic and acyclic diols is demonstrated by various examples.

引用

页码：517 / 536

页数：20

共 110 条

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