A NEW ASYMMETRIC-SYNTHESIS OF TRICARBONYLCHROMIUM COMPLEXES OF ORTHO-SUBSTITUTED BENZALDEHYDES

被引：40

作者：

KUNDIG, EP

LIU, RG

RIPA, A

机构：

[1] Départment de Chimie Organique, Université de Genève, Genève, CH-1211, 30, quai Ernest-Ansermet

来源：

HELVETICA CHIMICA ACTA | 1992年 / 75卷 / 08期

关键词：

D O I：

10.1002/hlca.19920750818

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

ortho-Substituted [Cr(CO)3(benzaldehyde)) complexes are obtained via nucleophilic addition of alkyl- and aryllithium reagents to a [Cr(CO)3(phenylmethaneimine)] complex followed by endo-hydride abstraction with triphenylmethyl cation. This sequence, when carried out with a [Cr(CO)3(benzaldehyde SAMP hydrazone)] complex affords substituted derivatives (Me, Bu, Ph, vinyl) with high ( greater-than-or-equal-to 97 %) diastereoselectivity and, after hydrolysis, ortho-substituted [Cr(CO)3(benzaldehyde)] ((S)-1) complexes of high enantiomeric purity.

引用

页码：2657 / 2660

页数：4

共 39 条

[21]

KUNDIG EP, 1991, J AM CHEM SOC, V113, P9676

[22]

KUNDIG EP, 1991, SYNLETT, V2, P657

[23] ENZYMATIC GENERATION OF PLANAR CHIRALITY IN THE (ARENE)TRICARBONYLCHROMIUM SERIES [J].