INHIBITION OF AN ENDOGENOUS GROWTH-RELATED PROTEINASE ENHANCES THE RECOVERY OF A NEGATIVE GROWTH-REGULATOR FROM CULTURED HUMAN-CELLS

被引：10

作者：

MANILAL, S

SCOTT, GK

TSE, CA

机构：

[1] Department of Biochemistry, University of Auckland, Auckland

来源：

CELL BIOLOGY INTERNATIONAL | 1993年 / 17卷 / 03期

关键词：

D O I：

10.1006/cbir.1993.1067

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The possibility that a growth-related proteinase may act by degrading a negative growth regulatory protein has been investigated. Proteinase inhibitors which inhibit the enzyme also enhance the accumulation of the growth regulator by human fibroblasts. The negative growth regulator shows a similar specificity of inhibition of cellular growth to inhibitors of the growth-related proteinase. © 1993 Academic Press. All rights reserved.

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页码：317 / 323

页数：7

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