METHOTREXATE ANALOGS .26. INHIBITION OF DIHYDROFOLATE-REDUCTASE AND FOLYLPOLYGLUTAMATE SYNTHETASE-ACTIVITY AND INVITRO TUMOR-CELL GROWTH BY METHOTREXATE AND AMINOPTERIN ANALOGS CONTAINING A BASIC-AMINO-ACID SIDE-CHAIN

被引：58

作者：

ROSOWSKY, A

FREISHEIM, JH

MORAN, RG

SOLAN, VC

BADER, H

WRIGHT, JE

RADIKESMITH, M

机构：

[1] HARVARD UNIV,SCH MED,DEPT PHARMACOL,BOSTON,MA 02115

[2] MED COLL OHIO,DEPT BIOCHEM,TOLEDO,OH 43699

[3] CHILDRENS HOSP,DIV HEMATOL ONCOL,LOS ANGELES,CA 90027

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1986年 / 29卷 / 05期

关键词：

D O I：

10.1021/jm00155a012

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：655 / 660

页数：6

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