THERMODYNAMIC CHARACTERIZATION OF THE INTERACTIONS OF METHOTREXATE WITH DIHYDROFOLATE-REDUCTASE BY QUANTITATIVE AFFINITY-CHROMATOGRAPHY

被引：8

作者：

WALTHAM, MC

HOLLAND, JW

NIXON, PF

WINZOR, DJ

机构：

[1] UNIV QUEENSLAND,DEPT BIOCHEM,ST LUCIA,QLD 4067,AUSTRALIA

[2] PRINCESS ALEXANDRA HOSP,WOOLOONGABBA,QLD 4102,AUSTRALIA

来源：

BIOCHEMICAL PHARMACOLOGY | 1988年 / 37卷 / 03期

关键词：

D O I：

10.1016/0006-2952(88)90226-2

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：541 / 545

页数：5

共 10 条

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[8] DIRECT EXPERIMENTAL-EVIDENCE FOR COMPETITIVE-INHIBITION OF DIHYDROFOLATE-REDUCTASE BY METHOTREXATE [J].

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[9] METHOTREXATE, A HIGH-AFFINITY PSEUDOSUBSTRATE OF DIHYDROFOLATE-REDUCTASE [J].

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